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Cat. No.: HY-182718

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AZD0011-PL

AZD0011-PL is a human arginase 1/ 2 inhibitor with IC₅₀ values of 0.01 μM and 0.02 μM. AZD0011-PL can be used for the researches of cancer, respiratory inflammatory disease.

For research use only. We do not sell to patients.

CAS No.: 2374807-39-1
Formula: C₉H₁₉BN₂O₄
Molecular Weight:230.07

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

AZD0011-PL Chemical Structure

CAS No.: 2374807-39-1

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Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- IC₅₀ & Target
- In Vitro
Chemical Information
Purity & Documentation
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

Description

AZD0011-PL is a human arginase 1/ 2 inhibitor with IC₅₀ values of 0.01 μM and 0.02 μM. AZD0011-PL can be used for the researches of cancer, respiratory inflammatory disease^[1].

IC₅₀ & Target^[1]

hArginase 1

0.01 μM (IC₅₀)

hArginase 2

0.02 μM (IC₅₀)

In Vitro

AZD0011-PL (Compound 7) potently inhibits recombinant human Arginase 1 with an IC₅₀ of 0.01 μM and recombinant human Arginase 2 with an IC₅₀ of 0.02 μM^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS No. 2374807-39-1
Molecular Weight 230.07
Formula C₉H₁₉BN₂O₄
SMILES

OB(O)CCCC[C@]1(NC[C@@H](C1)N)C(O)=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Handling Instructions (2659 KB)

References

[1]. Scott Nathan MLYNARSKI, et al. Arginase inhibitors and methods of use thereof. WO2019159120A1. 2020-08-17

Calculators

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Dilution Calculator

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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