Polyaminopropyl biguanide
Based on 1 Customer Validation
Polyaminopropyl biguanide (PAPB) is a positively charged antimicrobial polymer and cosmetic preservative. Polyaminopropyl biguanide inhibits the growth and division of negatively charged microorganisms via charge-based adsorption. Polyaminopropyl biguanide exhibits broad-spectrum in vitro activity against foodborne microorganisms and postharvest fruit pathogens. Polyaminopropyl biguanide can be used in studies related to citrus postharvest diseases and foodborne bacterial infections.
For research use only. We do not sell to patients.
- CAS No.: 133029-32-0
- Formula: (C5H14N6)n
-
Storage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
-
Biological Activity
-
Chemical Information
-
Solvent & Solubility
- Purity & Documentation
- References
-
Help & FAQs
Biological Activity
Polyaminopropyl biguanide (0.125-0.25%) significantly enhances the tensile strength and elongation at break of PEC/PVA composite films, with the 0.25% formulation exhibiting the highest tensile strength of up to 26.90 MPa[2].
Polyaminopropyl biguanide (0.125-1%) reduces the diffraction peak intensity of PEC/PVA composite films and improves their thermal stability in a concentration-dependent manner[2].
The polyaminopropyl biguanide/PEC/PVA composite films (0.125-1%) exhibit potent in vitro antibacterial activity, including 100% inhibition of Penicillium italicum at a polyaminopropyl biguanide concentration of 0.125%, and show stronger activity against Staphylococcus aureus than against Escherichia coli[2].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
-
CAS No. 133029-32-0
-
Appearance Solid
-
Formula (C5H14N6)n
-
Color White to off-white
-
SMILES
N=C(NC(NCCCN)=N)N.[n]
-
Synonyms
PAPB
-
Shipping
Room temperature in continental US; may vary elsewhere.
-
Storage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
DMSO : 50 mg/mL (Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Purity & Documentation
-
Data Sheet (266 KB)
-
SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
-
Handling Instructions (2659 KB)
References
[1]. Scientific Committee on Consumer Safety; Bernauer U. Opinion of the scientific committee on consumer safety (SCCS)--2nd Revision of the safety of the use of poly(hexamethylene) biguanide hydrochloride or polyaminopropyl biguanide (PHMB) in cosmetic products. Regul Toxicol Pharmacol. 2015 Dec;73(3):885-6. [Content Brief]
[2]. He M, et al. Fabrication of antimicrobial packaging based on polyaminopropyl biguanide incorporated pectin/polyvinyl alcohol films for fruit preservation. Food Chem. 2024;457:140106. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Polyaminopropyl biguanide Related Classifications
HY-158761 Related Classifications
Powered by Bioz
- Polyaminopropyl biguanide
- 133029-32-0
- PAPB
- Bacterial
- P. italicum
- post-harvest fruit pathogens
- PEC/PVA composite films
- Penicillium italicum
- foodborne bacterial infections
- citrus post-harvest disease
- Escherichia coli
- Staphylococcus aureus
- food-borne microorganisms
- pectin/polyvinyl alcohol films
- Inhibitor
- inhibitor
- inhibit