1-Aminoindan
Based on 1 Customer Validation
1-Aminoindan (1-Indanamine; 2,3-Dihydro-1H-inden-1-amine) is an α-synuclein (α-synuclein) binder. By binding to α-synuclein, 1-Aminoindan promotes the formation of its neuroprotective "cyclic" conformation, thereby reducing the misfolding and aggregation of α-synuclein. 1-Aminoindan is a metabolite of Rasagiline (HY-14605A). 1-Aminoindan can be used in research related to Parkinson's disease.
For research use only. We do not sell to patients.
- Purity: 99.29%
- CAS No.: 34698-41-4
- Formula: C9H11N
- Molecular Weight:133.19
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Storage:
4°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
All α-synuclein Isoforms
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Biological Activity
1-Aminoindan binds to the soluble monomeric structures of C1, C4, C5 and C8 of α-synuclein, and induces the formation of a neuroprotective "circular" conformation, thereby reducing the misfolding and aggregation of α-synuclein[2].
1-Aminoindan binds to distinct sites on human adenosine A1 and A2a receptors, and interacts with residues F171, L250, I274, I270 and N254 of A1R, as well as residues F163, E164, L244, M265 and I269 of A2aR[2].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 34698-41-4
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Appearance Liquid (Density: 1.038 g/cm3)
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Molecular Weight 133.19
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Formula C9H11N
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Color Colorless to light yellow
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SMILES
NC1C2=C(CC1)C=CC=C2
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Synonyms
1-Indanamine; 2,3-Dihydro-1H-inden-1-amine
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
4°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
Purity & Documentation
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Data Sheet (272 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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Handling Instructions (2659 KB)
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
1-Aminoindan Related Classifications
HY-W007551 Related Classifications
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