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LY 345899 

Cat. No.: HY-101943
Handling Instructions

LY 345899 is a human cytosolic methylenetetrahydrofolate dehydrogenase/cyclohydrolase (DC301) inhibitor, with a Ki of 0.018 μM.

For research use only. We do not sell to patients.

LY 345899 Chemical Structure

LY 345899 Chemical Structure

CAS No. : 10538-99-5

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  • Biological Activity

  • Technical Information

  • Purity & Documentation

  • References

Description

LY 345899 is a human cytosolic methylenetetrahydrofolate dehydrogenase/cyclohydrolase (DC301) inhibitor, with a Ki of 0.018 μM.

IC50 & Target

Ki: 0.018 μM (DC301)[1].

Solvent & Solubility
In Vitro: 

10 mM in DMSO

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.1213 mL 10.6063 mL 21.2125 mL
5 mM 0.4243 mL 2.1213 mL 4.2425 mL
10 mM 0.2121 mL 1.0606 mL 2.1213 mL
*Please refer to the solubility information to select the appropriate solvent.
References
Molecular Weight

471.42

Formula

C₂₀H₂₁N₇O₇

CAS No.

10538-99-5

SMILES

O=C(O)[[email protected]@H](NC(C1=CC=C(N2C(N3C4=C(NC(N)=NC4=O)NCC3C2)=O)C=C1)=O)CCC(O)=O

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Shipping

Room temperature in continental US; may vary elsewhere

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This equation is commonly abbreviated as: C1V1 = C2V2

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C1   V1   C2   V2

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Product Name:
LY 345899
Cat. No.:
HY-101943
Quantity:

LY 345899

Cat. No.: HY-101943