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Mannose-PEG3400-COOH is a conjugate composed of mannose, PEG chains, and carboxyl groups (COOH). Mannose-PEG-COOH combines the targeting recognition ability of mannose with the carboxyl group, which can undergo condensation or esterification reactions with amino and hydroxyl groups, for applications such as targeted drug delivery systems and nanoparticle modification.

Mannose-PEG5000-COOH is a conjugate composed of mannose, PEG chains, and carboxyl groups (COOH). Mannose-PEG-COOH combines the targeting recognition ability of mannose with the carboxyl group, which can undergo condensation or esterification reactions with amino and hydroxyl groups, for applications such as targeted drug delivery systems and nanoparticle modification.

Mannose-PEG10000-COOH is a conjugate composed of mannose, PEG chains, and carboxyl groups (COOH). Mannose-PEG-COOH combines the targeting recognition ability of mannose with the carboxyl group, which can undergo condensation or esterification reactions with amino and hydroxyl groups, for applications such as targeted drug delivery systems and nanoparticle modification.

JNK1 ligand-1 is a JNK1 ligand that can be used for the synthesis of PROTACs, such as PROTAC JNK1 degrader-1 (HY-182796).

CRBN ligand-901 (5d in Scheme 2) is a ligand for Cereblon (CRBN). CRBN ligand-901 can be linked to target protein ligands (e.g., VP1 ligand-1) via a linker to form PROTAC molecules (e.g., Jun15702 (HY-182924)).

VP1 ligand-Linker Conjugate 1 is a target protein ligand-linker conjugate that can be used for the synthesis of PROTACs, such as Jun15702 (HY-182924).

Mannose-PEG1000-NH2 is composed of mannose, PEG chains, and terminal amino groups (–NH2). Mannose-PEG-NH2 combines the targeting recognition ability of mannose with the chemical modifiability of amino groups, making it suitable for applications such as targeted drug delivery systems and nanoparticle modification.

Mannose-PEG2000-NH2 is composed of mannose, PEG chains, and terminal amino groups (–NH2). Mannose-PEG-NH2 combines the targeting recognition ability of mannose with the chemical modifiability of amino groups, making it suitable for applications such as targeted drug delivery systems and nanoparticle modification.

Mannose-PEG3400-NH2 is composed of mannose, PEG chains, and terminal amino groups (–NH2). Mannose-PEG-NH2 combines the targeting recognition ability of mannose with the chemical modifiability of amino groups, making it suitable for applications such as targeted drug delivery systems and nanoparticle modification.

Mannose-PEG5000-NH2 is composed of mannose, PEG chains, and terminal amino groups (–NH2). Mannose-PEG-NH2 combines the targeting recognition ability of mannose with the chemical modifiability of amino groups, making it suitable for applications such as targeted drug delivery systems and nanoparticle modification.

Mannose-PEG10000-NH2 is composed of mannose, PEG chains, and terminal amino groups (–NH2). Mannose-PEG-NH2 combines the targeting recognition ability of mannose with the chemical modifiability of amino groups, making it suitable for applications such as targeted drug delivery systems and nanoparticle modification.

DMPE-PEG1000-NHS is a conjugate composed of DMPE, PEG chains, and terminal active esters (NHS). The NHS ester in DMPE-PEG1000-NHS can rapidly covalently react with molecules containing primary amines (such as proteins, peptides, and small molecules modified with amino groups) to form stable amide bonds, enabling targeted modification of liposomes/nanoparticles.

DMPE-PEG2000-NHS is a conjugate composed of DMPE, PEG chains, and terminal active esters (NHS). The NHS ester in DMPE-PEG2000-NHS can rapidly covalently react with molecules containing primary amines (such as proteins, peptides, and small molecules modified with amino groups) to form stable amide bonds, enabling targeted modification of liposomes/nanoparticles.

DMPE-PEG3400-NHS is a conjugate composed of DMPE, PEG chains, and terminal active esters (NHS). The NHS ester in DMPE-PEG3400-NHS can rapidly covalently react with molecules containing primary amines (such as proteins, peptides, and small molecules modified with amino groups) to form stable amide bonds, enabling targeted modification of liposomes/nanoparticles.

DMPE-PEG5000-NHS is a conjugate composed of DMPE, PEG chains, and terminal active esters (NHS). The NHS ester in DMPE-PEG5000-NHS can rapidly covalently react with molecules containing primary amines (such as proteins, peptides, and small molecules modified with amino groups) to form stable amide bonds, enabling targeted modification of liposomes/nanoparticles.

DMPE-PEG10000-NHS is a conjugate composed of DMPE, PEG chains, and terminal active esters (NHS). The NHS ester in DMPE-PEG10000-NHS can rapidly covalently react with molecules containing primary amines (such as proteins, peptides, and small molecules modified with amino groups) to form stable amide bonds, enabling targeted modification of liposomes/nanoparticles.

N-Descyclopropanecarbaldehyde olaparib-CO-C9-NHBoc (Compound 6h) is a target protein ligand-linker conjugate that can be used for the synthesis of PROTACs, such as PROTAC PARP2 degrader-1 (HY-183013).

mPEG300-Mannose is a polymeric derivative formed by the chemical coupling of methoxy polyethylene glycol (mPEG) and mannose. mPEG300-Mannose combines the biocompatibility of polyethylene glycol with the specificity of mannose in biorecognition, and is widely used in fields such as biomaterial modification and targeted delivery systems.

mPEG500-Mannose is a polymeric derivative formed by the chemical coupling of methoxy polyethylene glycol (mPEG) and mannose. mPEG500-Mannose combines the biocompatibility of polyethylene glycol with the specificity of mannose in biorecognition, and is widely used in fields such as biomaterial modification and targeted delivery systems.

mPEG550-Mannose is a polymeric derivative formed by the chemical coupling of methoxy polyethylene glycol (mPEG) and mannose. mPEG550-Mannose combines the biocompatibility of polyethylene glycol with the specificity of mannose in biorecognition, and is widely used in fields such as biomaterial modification and targeted delivery systems.