Others

2-Hydroxy-3-(4-methylphenyl)propanoic acid-d₃ is deuterium-labeled 2-Hydroxy-3-(4-methylphenyl)propanoic acid (HY-W185139).

Chloridazon metabolite B1-d₃ (Methyldesphenylchloridazon-d₃) is deuterium labeled 5-Amino-4-chloro-2-methyl-2,3-dihydropyridazin-3-one.

Ketoprofen impurity 7 is an impurity of Ketoprofen.

Tamsulosin impurity 17 is an impurity of Tamsulosin.

Homarylamine hydrochloride is structurally categorized as a phenethylamine.

2-Mercaptopyridin-3-ol (3-HPT) is a natural product with strong metal coordination ability. 2-Mercaptopyridin-3-ol can be used as a metal enzyme inhibitor.

2-[Methyl(nitroso)amino]acetic acid-d₃ is the deuterium labeled 2-[methyl(nitroso)amino]acetic acid.

4-(Pyrrolidin-1-yl)butanoic acid hydrochloride is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

Mesalazine impurity 10 (N-Propionyl Mesalazine) is an impurity of Mesalazine.

(1-Benzylpiperidin-3-yl)methanol is a pharmaceutical intermediate that can be used to synthesize compounds that can be used to study Alzheimer's disease (AD).

Fmoc-NH-PEG4-HZ-BOC is a PEG reagent containing an Fmoc-protected amine and a Boc-protected hydrazide. The Fmoc group can be deprotected under basic condition to obtain the free amine which can be used for further conjugations. The hydrophilic PEG spacer increases solubility in aqueous media. The Boc can be deprotected under mild acidic conditions to form a reactive hydrazide, which can then be coupled with various carbonyl groups.

Azide-PEG8-Tos is a small PEG linker featuring an azide and a tosylate. Tosylates are good leaving groups which are easily displaced by nucleophiles while azide is a click chemistry motif which is used to react with terminal alkynes or strained cyclooctynes.

BocNH-PEG8-CH2CH2COONHS is a PEG linker containing an NHS ester and a Boc-protected amino group. The hydrophilic PEG spacer increases the water solubility of a compound in aqueous media. The Boc group can be deprotected under mild acidic conditions to form a free amine. The NHS ester can be used to label the primary amines (-NH2) of proteins, amine-modified oligonucleotides, and other amine-containing molecules.

Amino-PEG11-t-butyl ester is a PEG reagent containing an amino NH2 group with a t-butyl protected carboxyl group (Boc). Amino-PEG11-t-butyl ester can be used in drug delivery research.

Tos-PEG11-t-butyl ester is a PEG linker containing a t-butyl ester and a tosyl group. The hydrophilic PEG spacer increases solubility in aqueous media. The t-butyl protected carboxyl group can be deprotected under acidic conditions. The tosyl group is a very good leaving group for nucleophilic substitution reactions.

2-Amino-1,3-bis(tert-butyldimethylsilanoxy)propane has a TBDMS, acid labile protecting group. TBDMS is used for the protection of alcohol groups. The primary amine is able to react with carboxylic acids, active NHS esters and other carbonyl compounds.

6-(tert-Butoxy)-6-oxohexanoic NHS ester has a t-butyl ester group and an NHS ester moiety. The t-butyl group can be deprotected under acidic conditions. NHS ester can react specifically and efficiently with primary amines such as the side chain of lysine residues or aminosilane-coated surfaces at neutral or slightly basic condition to form a covalent bond.

Trifluoroacetamidoethyl-SS-propionic NHS ester is a cleavable linker containing an NHS ester. The NHS ester can be used to label the primary amines (-NH2) of proteins, amine-modified oligonucleotides, and other amine-containing molecules. The disulfide bond can be cleaved under reduction conditions.

Desthiobiotin-PEG3-NHS ester is a single-ring, sulfur-free analog of biotin that binds to streptavidin with nearly equal specificity but less affinity than biotin (K_d = 1011 vs. 1015 M, respectively). Consequently, desthiobiotinylated proteins can be eluted readily and specifically from streptavidin affinity resin using mild conditions based on competitive displacement with free biotin.

AZD-PEG2-acid is a PEG linker containing an AZD group and a terminal carboxylic acid. The hydrophilic PEG spacer increases solubility in aqueous media. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond.