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Cat. No.: HY-W187463

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2-Mercaptopyridin-3-ol

(Synonyms: 3-HPT)

2-Mercaptopyridin-3-ol (3-HPT) is a natural product with strong metal coordination ability. 2-Mercaptopyridin-3-ol can be used as a metal enzyme inhibitor.

For research use only. We do not sell to patients.

CAS No.: 23003-22-7
Formula: C₅H₅NOS
Molecular Weight:127.16

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (270 KB)

2-Mercaptopyridin-3-ol Chemical Structure

CAS No.: 23003-22-7

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Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- Cellular Effect
Chemical Information
Purity & Documentation
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

Description

2-Mercaptopyridin-3-ol (3-HPT) is a natural product with strong metal coordination ability. 2-Mercaptopyridin-3-ol can be used as a metal enzyme inhibitor^[1].

Cellular Effect

Cell Line	Type	Value	Description	References
THP-1	IC₅₀	>10 μg/mL Compound: 1b	Cytotoxicity against human THP1 cells after 48 hrs by Alamar blue assay Cytotoxicity against human THP1 cells after 48 hrs by Alamar blue assay	[PMID: 25240614]
THP-1	IC₅₀	6.1 μg/mL Compound: 1b	Antileishmanial activity against amastigote stage of Leishmania donovani infected in human THP1 cells after 48 hrs by Alamar blue assay Antileishmanial activity against amastigote stage of Leishmania donovani infected in human THP1 cells after 48 hrs by Alamar blue assay	[PMID: 25240614]

Chemical Information

CAS No. 23003-22-7
Molecular Weight 127.16
Formula C₅H₅NOS
SMILES

S=C1NC=CC=C1O
Synonyms

3-HPT
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (270 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Adamek RN, et al. Isosteres of hydroxypyridinethione as drug-like pharmacophores for metalloenzyme inhibition. J Biol Inorg Chem. 2018 Oct;23(7):1129-1138.

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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