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Isotope-Labeled Compounds
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Isotope-Labeled Compounds Related Products (11047)
Related Products (11047)
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NSC 1940-d8
0 ImagesCat. No.: HY-Y0226S1CAS No.: 1219799-33-3NSC 1940-d8 is the deuterium labeled NSC 1940. -
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Aeruginascin-d8
0 ImagesCat. No.: HY-169896SAeruginascin-d3 is deuterium labeled Aeruginascin. -
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Sitagliptin-d6
0 ImagesCat. No.: HY-13749S3CAS No.: 1133211-99-0Synonyms: MK-0431-d6Sitagliptin-d6 (MK-0431-d6) is deuterium labeled Sitagliptin (HY-13749). Sitagliptin is an orally active and highly selective DPP4 inhibitor with an IC50 value of 19 nM. Sitagliptin blocks the degradation of glucagon-like peptide-1 (GLP-1) and glucose-dependent insulinotropic peptide (GIP) by competing inhibition mechanism (Kᵢ = 1 nM), thereby increasing the level of active incretin. Sitagliptin can also directly stimulate the secretion of GLP-1 by intestinal L cells by activating the cAMP/PKA and ERK1/2 pathways, and this effect is independent of DPP-4. Sitagliptin shows protective effects on pancreatic islet grafts in 1-type diabetes models. Sitagliptin can be used for the study of 1-type and 2-type diabetes. -
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Fmoc-Arg(Pbf)-OH-13C6
0 ImagesCat. No.: HY-Y1636S1Fmoc-Arg(Pbf)-OH-13C6 is the 13C labeled Fmoc-Arg(Pbf)-OH. Fmoc-Arg(Pbf)-OH is an arginine derivative containing amine protecting group Fmoc. Fmoc-Arg(Pbf)-OH is a building block for the introduction of Arg into SPPS (Solid-Phase Peptide Synthesis). -
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(rel)-Saxagliptin-13C,d2 TFA
0 ImagesCat. No.: HY-10285S1CAS No.: 2012595-09-2Synonyms: (rel)-BMS-477118-13C,d2 TFA(rel)-Saxagliptin-13C,d2 ((rel)-BMS-477118-13C,d2) TFA is 13C-labeled Saxagliptin (HY-10285). -
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Triundecanoin-d5
0 ImagesCat. No.: HY-W745615Triundecanoin-d5 is the deuterium labeled Triundecanoin. -
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alpha-D-glucose-13C6,d7
0 ImagesCat. No.: HY-128417S5alpha-D-glucose-13C6,d7 is deuterium and 13C-labeled alpha-D-glucose (HY-128417). alpha-D-glucose is an endogenous metabolite. -
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1,2-Bis(pentabromophenyl)ethane-13C14
0 ImagesCat. No.: HY-W013058S1,2-Bis(pentabromophenyl)ethane-13C14 is 13C labeled 1,2-Bis(perbromophenyl)ethane. -
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BOC-L-phenylalanine-d5
0 ImagesCat. No.: HY-79096S1CAS No.: 121695-40-7BOC-L-phenylalanine-d5 is the deuterium labeled BOC-L-phenylalanine (HY-79096). Boc-L-phenylalanine is a Boc-protected L-phenylalanine that can be used in the synthesis of other active compounds. Boc-L-phenylalanine is also a capping agent. -
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Desmethylcerivastatin-d7 sodium
0 ImagesCat. No.: HY-154780SDesmethylcerivastatin-d7 sodium is deuterated labeled Desmethylcerivastatin. -
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3-Hydroxy desloratadine-d6
0 ImagesCat. No.: HY-124245S23-Hydroxy desloratadine-d6 is deuterated labeled 3-Hydroxy desloratadine (HY-124245). 3-Hydroxy desloratidine is a metabolite of Desloratidine. -
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Acetamiprid-N-desmethyl-13C,d3
0 ImagesCat. No.: HY-W753602Acetamiprid-N-desmethyl-13C,d3 is the 13C and deuterium labeled isotope of Acetamiprid-N-desmethyl(13C,d3)(HY-B0823).Acetamiprid is a nAChR agonist that has been implicated in neuromuscular and reproductive disorders. -
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Glibenclamide-13C6
0 ImagesCat. No.: HY-15206S2Synonyms: Glyburide-13C6Glibenclamide-13C6 (Glyburide-13C6) is 13C labeled Glibenclamide. Glibenclamide (Glyburide) is an orally active ATP-sensitive K+ channel (KATP) inhibitor and can be used for the research of diabetes and obesity. Glibenclamide inhibits P-glycoprotein. Glibenclamide directly binds and blocks the SUR1 subunits of KATP and inhibits the cystic fibrosis transmembrane conductance regulator protein (CFTR). Glibenclamide interferes with mitochondrial bioenergetics by inducing changes on membrane ion permeability. Glibenclamide can induce autophagy. -
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1-Octanol-d5
0 ImagesCat. No.: HY-W032013S3CAS No.: 3028869-76-0Synonyms: Octanol-d51-Octanol-d5 is deuterated labeled 1-Octanol (HY-W032013). 1-Octanol (Octanol), a saturated fatty alcohol, is a T-type calcium channels (T-channels) inhibitor with an IC50 of 4 μM for native T-currents. 1-Octanol is a highly attractive biofuel with diesel-like properties. -
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Hypoxanthine-13C2,15N-1
0 ImagesCat. No.: HY-N0091S4CAS No.: 1246820-04-1Synonyms: Purin-6-ol-13C2,15N-1; Sarcine-13C2,15N-1Hypoxanthine-13C2,15N-1 is a 15N-labeled and 13C-labled Hypoxanthine (HY-N0091). Hypoxanthine, a purine derivative, is a potential free radical generator and could be used as an indicator of hypoxia. -
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Irbesartan-d7
0 ImagesCat. No.: HY-B0202S3Synonyms: SR-47436-d7; BMS-186295-d7Irbesartan-d7 is deuterated labeled Irbesartan (HY-B0202). Irbesartan (SR-47436) is an orally active Ang II type 1 (AT1) receptor blocker (ARB). Irbesartan can relax the blood vessels, low blood pressure and increase the supply of blood and oxygen to the heart. Irbesartan can be used for the research of high blood pressure, heart failure, and diabetic kidney disease. -
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3-Phenyl-9H-carbazole-d12
0 ImagesCat. No.: HY-W103764S1CAS No.: 2851075-04-03-Phenyl-9H-carbazole-d12 is the deuterium labeled 3-Phenyl-9H-carbazole. -
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Bis(1-chloro-2-propyl) phosphate-d12
0 ImagesCat. No.: HY-W653929CAS No.: 1870073-89-4Synonyms: BCIPP-d12Bis(1-chloro-2-propyl) phosphate-d12 is deuterium labeled Bis(1-chloro-2-propyl) phosphate. Bis(1-chloro-2-propyl) phosphate (BCIPP) is a metabolite of organophosphate flame retardants (OPFR) that may alter energy metabolism by influencing the levels of steroid hormones, such as cortisol and cortisone. Bis(1-chloro-2-propyl) phosphate holds potential for research on metabolism-related diseases caused by environmental exposure. -
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N-6-[rel-(2R,6S)-2,6-Dimethyl-4-morpholinyl]-3-pyridinamine-Sonidegib-d8
0 ImagesCat. No.: HY-157571S -
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Epi lovastatin-d3
0 ImagesCat. No.: HY-N0504SCAS No.: 1330264-51-1Epi Lovastatin-d3 is the deuterium labeled Lovastatin. Lovastatin is a cell-permeable HMG-CoA reductase inhibitor used to lower cholesterol. -
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