3-Hydroxy desloratadine-d6
3-Hydroxy desloratadine-d6 is deuterated labeled 3-Hydroxy desloratadine (HY-124245). 3-Hydroxy desloratidine is a metabolite of Desloratidine.
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- Fòrmula: C19H13D6ClN2O
- Peso molecular:332.86
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Almacenamiento:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Actividad biológica
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Chemical Information
- Pureza y Documentación
- Referencias
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Help & FAQs
Actividad biológica
Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Chemical Information
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Unlabeled Cas 119410-08-1
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Peso molecular 332.86
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Fòrmula C19H13D6ClN2O
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SMILES
ClC1=CC=C(C(C([2H])([2H])CC2=CC(O)=CN=C2/3)=C1)C3=C4C([2H])C([2H])NC([2H])C\4[2H]
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureza y Documentación
Referencias
[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216. [Content Brief]
[2]. Melton Affrime, et al. A pharmacokinetic profile of desloratadine in healthy adults, including elderly. Clin Pharmacokinet. 2002;41 Suppl 1:13-9. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
3-Hydroxy desloratadine-d6 Related Classifications
HY-124245S2 Related Classifications
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