3-Hydroxy desloratadine-d6
3-Hydroxy desloratadine-d6 is deuterated labeled 3-Hydroxy desloratadine (HY-124245). 3-Hydroxy desloratidine is a metabolite of Desloratidine.
For research use only. We do not sell to patients.
- Formula: C19H13D6ClN2O
- Molecular Weight:332.86
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Chemical Information
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Unlabeled Cas 119410-08-1
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Molecular Weight 332.86
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Formula C19H13D6ClN2O
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SMILES
ClC1=CC=C(C(C([2H])([2H])CC2=CC(O)=CN=C2/3)=C1)C3=C4C([2H])C([2H])NC([2H])C\4[2H]
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216. [Content Brief]
[2]. Melton Affrime, et al. A pharmacokinetic profile of desloratadine in healthy adults, including elderly. Clin Pharmacokinet. 2002;41 Suppl 1:13-9. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
3-Hydroxy desloratadine-d6 Related Classifications
HY-124245S2 Related Classifications
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