Liposome
Liposomes (NPs typically 100–500 nm in diameter) are fabricated from the self-assembly of phospholipids, which consist of a polar phosphate head group and hydrophobic lipid tails. In aqueous environments, the hydrophobic tails self-orient, resulting in a spherical structure comprised of an aqueous core surrounded by a lipophilic bilayer membrane. Liposomes are both biocompatible and biodegradable (e.g., at certain pH and temperature), which can be controlled by modifying the lipid composition. Furthermore, liposomes are amenable to various modifications that improve their efficacy as drug delivery carriers.
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Liposome Related Products (1076)
Related Products (1076)
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DSPE-PEG2000-Mal-Cys-YEQDPWGVKWWY
0 ImagesCat. No.: HY-172273ADSPE-PEG2000-Mal-Cys-YEQDPWGVKWWY is a PEG compound which composed of DSPE and a M2-polarized macrophages targeting peptide (M2pep, YEQDPWGVKWWY). M2pep is conjugated to a proapoptotic peptide as monovalent or multivalent ligands to concentrate the toxic effect of the peptide to M2 macrophages. DSPE-PEG2000-Mal-Cys-YEQDPWGVKWWY can be used for drug delivery.
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1-Palmitoyl-2-10-pahsa-3-oleoyl-sn-glycerol
0 ImagesCat. No.: HY-173548Synonyms: 16:0-10-Pahsa-18:1-TG1-Palmitoyl-2-10-pahsa-3-oleoyl-sn-glycerol (16:0-10-Pahsa-18:1-TG) is a triacylglycerol that contains Palmitic acid (HY-N08307), the fatty acid ester of hydroxy fatty acid (FAHFA) 10-PAHSA, and Oleic acid (HY-N1446).
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1-Thio-β-D-glucose Sodium Salt Dihydrate-13C6
0 ImagesCat. No.: HY-W7484181-Thio-β-D-glucose Sodium Salt Dihydrate-13C6 is the 13C-labeled 1-Thio-β-D-glucose sodium (HY-115419). 1-Thio-β-D-glucose sodium is the sodium salt form of 1-Thio-β-D-glucose. 1-Thio-β-D-glucose forms hydrophilic self-assembled monolayer with metal, stablizes the lipid bilayer and protects the proteins from denaturation.
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DSPE-PEG3400-NGR
0 ImagesCat. No.: HY-172473ADSPE-PEG34000-NGR is a PEG compound which composed of DSPE and an Asn-Gly-Arg (NGR) peptide. NGR peptide can target tumor vascular antigen CD13. DSPE-PEG3400-NGR can be used for drug delivery.
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DPPE-PEG750
0 ImagesCat. No.: HY-144012CCAS No.: 474922-84-4Synonyms: 16:0 PEG750 PE; 1,2-Dipalmitoyl-sn-glycero-3-phosphoethanolamine-N-[methoxy(polyethylene glycol)-750] ammoniumDPPE-PEG750 is a PEG lipid functional end group used in the synthesis of liposomes (LPs) for the design of conjugated polymer nanoparticles. Through biotin modification and carboxyl terminus, lipid nanoparticles (LNPs) further coupling with other biomolecules can be achieved. Functionalized nanoparticles can be used for targeted labeling of specific cellular proteins. With streptavidin as a linker, biotinylated PEG lipid-conjugated polymer nanoparticles are able to bind to biotinylated antibodies on cell surface receptors, yielding the utility of fluorescence-based imaging and sensing.
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DSPE-PEG1000-octreotide
0 ImagesCat. No.: HY-172280DSPE-PEG1000-Octreotide is a PEG compound which composed of DSPE and a Octreotide (HY-P0036). Octreotide is a somatostatin receptor agonist. Octreotide has antitumor activity, mediates apoptosis and may also be used in disease studies in acromegaly. DSPE-PEG1000-Octreotide can be used for drug delivery.
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Cho-Arg TFA
0 ImagesCat. No.: HY-138912CAS No.: 1609010-56-1Cho-Arg TFA is a steroid-based cationic lipid with an L-Arginine headgroup. Cho-Arg TFA shows a remarkably high optimized plasmid DNA transfection efficacy.
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O12-D3-I3
0 ImagesCat. No.: HY-172328O12-D3-I3 is an ionizable cationic lipid. O12-D3-I3 can be used in the generation of lipid nanoparticles (LNPs) for siRNA delivery in vitro and in vivo. LNPs containing O12-D3-I3 enhances LNP endosomal escape for ferroptosis RNAi therapy of cancer.
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Cholesterol-PEG2000-Folate
0 ImagesCat. No.: HY-W440715Cholesterol-PEG2000-Folate is an excipient and can be used for the preparation of folate-conjugated PEG-liposomes.
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DSPC-d9
0 ImagesSynonyms: 1,2-Distearoyl-sn-glycero-3-PC-d9; 1,2-Distearoyl-sn-glycero-3-phosphorylcholine-d9DSPC-d9 (1,2-Distearoyl-sn-glycero-3-phosphorylcholine-d9) is the deuterium labeled DSPC (HY-W040193). DSPC is a cylindrical-shaped lipid. 1,2-Distearoyl-sn-glycero-3-phosphorylcholine is used to synthesize liposomes, and is the lipid component in the lipid nanoparticle (LNP) system.
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DSPE-PEG3400-CSTSMLKAC
0 ImagesCat. No.: HY-172687ADSPE-PEG3400-CSTSMLKAC is a PEG compound which composed of DSPE and a peptide (CSTSMLKAC). CSTSMLKAC is capable of mediating selective homing of phage to ischemic heart tissue. DSPE-PEG3400-CSTSMLKAC can be used for drug delivery.
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DOPG
0 ImagesCat. No.: HY-142980CAS No.: 62700-69-0Synonyms: DioleoylphosphatidylglycerolDOPG (Dioleoylphosphatidylglycerol) is a negatively charged phosphatidylglycerol phospholipid. DOPG is abundant in prokaryotic cell membranes and mitochondria, and has a low phase transition temperature and a tendency to form stable vesicles. DOPG inhibits the production of inflammatory mediators in macrophages in response to heat shock protein B4 (HSPB4)-activated toll-like receptor 2 (TLR2). DOPG is applicable to studies of membrane biology, drug-membrane interactions (especially in systems targeting negatively charged membranes), construction of drug delivery carriers, as well as research on sterile corneal inflammation and wound healing promotion.
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DSPE-PEG2000-Mal-Cys-RRRRRRRR
0 ImagesCat. No.: HY-172276ADSPE-PEG2000-R8 is a PEG compound which composed of DSPE and a cell-penetrating peptide (R8). pDSPE-PEG2000-R8 can be used for drug delivery.
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DSPE-PEG2000-K237
0 ImagesCat. No.: HY-172488DSPE-PEG2000-K237 is a PEG compound which composed of DSPE and a KDR targeting peptide (K237). K237 can functionally disrupt the interaction between VEGF and the KDR receptor and cause potent biological effects that include the inhibition of angiogenesis and tumor growth. DSPE-PEG2000-K237 can be used for drug delivery.
