Liposome
Liposomes (NPs typically 100–500 nm in diameter) are fabricated from the self-assembly of phospholipids, which consist of a polar phosphate head group and hydrophobic lipid tails. In aqueous environments, the hydrophobic tails self-orient, resulting in a spherical structure comprised of an aqueous core surrounded by a lipophilic bilayer membrane. Liposomes are both biocompatible and biodegradable (e.g., at certain pH and temperature), which can be controlled by modifying the lipid composition. Furthermore, liposomes are amenable to various modifications that improve their efficacy as drug delivery carriers.
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Liposome Related Products (1042)
Related Products (1042)
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CP-LC-1073
0 ImagesCat. No.: HY-W1130407CP-LC-1073 is a specific ionizable cationic amino lipid derived from the amino acid homocysteine. CP-LC-1073 can used in lipid nanoparticle (LNP) formulations for efficient in vivo delivery and expression of RNA (mRNA, cRNA, saRNA).
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18:1 Biotinyl PE
0 ImagesCat. No.: HY-W800796CAS No.: 384835-53-4Synonyms: 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine-N-(biotinyl)18:1 Biotinyl PE is a biotin-functionalized lipid attached to a phosphoethanolamine linked to two oleic acid groups.
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DSPE-PEG5000-Biotin
0 ImagesCat. No.: HY-140736BCAS No.: 385437-57-0DSPE-PEG5000-Biotin is a biotin-labeled PEG derivative composed of phospholipid (DSPE), a hydrophilic polyethylene glycol chain (PEG5000) and a biotin tag. DSPE-PEG5000-Biotin is widely used in scientific research for constructing targeted liposomes, micelles and lipid nanoparticles for drug delivery and cell binding experiments.
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DSPE-alkyne
0 ImagesCat. No.: HY-W440998CAS No.: 2933227-70-2DSPE-alkyne is a phospholipid. DSPE-alkyne is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
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CP-LC-0743
0 ImagesCat. No.: HY-172014CAS No.: 3040858-73-6CP-LC-0743 is an ionizable cationic amino lipid efficient delivery of different kinds of RNA (mRNA, cRNA and saRNA).
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DSPE-PEG5000-Rhodamine
0 ImagesCat. No.: HY-W440921DSPE-PEG5000-Rhodamine is a phospholipid polyPEG with red fluorescent. The polymer can form lipid bilayer and be used to prepare nanoparticles or liposomes for targeted drug delivery. Rhodamine has maximum absorption at 570 nm and emission around 595 nm and can be easily traced using an imaging technique.
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6,6′-Trehalose dioleate
0 ImagesCat. No.: HY-W1121519CAS No.: 338733-40-76,6′-Trehalose dioleate is a glycolipid that can be used to prepare lipid nanoparticles (LNPs) for drug delivery.
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Witepsol
0 ImagesCat. No.: HY-145782CAS No.: 91744-42-2Witepsol is a selective lipid-based vehicle for use in drug delivery systems.
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ALC-0315 (GMP Like)
0 ImagesALC-0315 (GMP Like) is ALC-0315 (HY-138170) produced by using GMP like guidelines. GMP Like small molecules works appropriately as an auxiliary reagent for cell therapy manufacture. ALC-0315 is an ionisable aminolipid that is responsible for mRNA compaction and aids mRNA cellular delivery and its cytoplasmic release through suspected endosomal destabilization. ALC-0315 can be used to form lipid nanoparticle (LNP) delivery vehicles. Lipid-Nanoparticles have been used in the research of mRNA COVID-19 vaccine.
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Stearic acid-PEG2000-FITC
0 ImagesCat. No.: HY-W440938Stearic acid-PEG2000-FITC is an amphiphatic polyPEG which can self assemble to form micelles in water. The polymer can be used to encapsulate therapeutic agent. FITC is a green dye with peak absorption at 494 nm and maximum emission at 520 nm and can be used for staining biological samples or nanoparticles. FITC can be easily traced by fluorescence microscopy.
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1-Palmitoyl-2-oleoyl-sn-glycero-3-PC-13C16
0 ImagesCat. No.: HY-130462S2CAS No.: 2692624-41-0Synonyms: POPC-13C161-Palmitoyl-2-oleoyl-sn-glycero-3-PC-13C16 (POPC-13C16) is 13C labeled 1-Palmitoyl-2-oleoyl-sn-glycero-3-PC. 1-Palmitoyl-2-oleoyl-sn-glycero-3-PC (POPC), a phospholipid, is a major component of biological membranes. 1-Palmitoyl-2-oleoyl-sn-glycero-3-PC is used for the preparation of liposomes and studying the properties of lipid bilayers.
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DMPE-PEG1000 ammonium
0 ImagesCat. No.: HY-155927CAS No.: 474922-82-2Synonyms: 14:0 PEG1000 PE ammonium; 1,2-Dimyristoyl-sn-glycero-3-phosphoethanolamine-N-[methoxy(polyethylene glycol)-1000] ammoniumDMPE-PEG1000 ammonium (14:0 PEG1000 PE ammonium) is a PEG lipid functional end group used in the synthesis of liposomes (LPs) for the design of conjugated polymer nanoparticles. Through biotin modification and carboxyl terminus, lipid nanoparticles (LNPs) further coupling with other biomolecules can be achieved. Functionalized nanoparticles can be used for targeted labeling of specific cellular proteins. With streptavidin as a linker, biotinylated PEG lipid-conjugated polymer nanoparticles are able to bind to biotinylated antibodies on cell surface receptors, yielding the utility of fluorescence-based imaging and sensing.
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1-Palmitoyl-2-oleoyl-sn-glycero-3-PS
0 ImagesSynonyms: 16:0-18:1 PS (POPS) free acid2-Oleoyl-1-palmitoyl-sn-glycero-3-phospho-L-serine (16:0-18:1 PS (POPS) free acid) is an anionic phospholipid with oleic acid (18:1) and palmitic acid (16:0) tails containing a carboxylic acid (COOH) and amine (NH2) in their head group. 2-Oleoyl-1-palmitoyl-sn-glycero-3-phospho-L-serine has been used in the preparation of lipid-mixing vesicles, liposomes, and artificial membranes.
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a12k4E-Ca
0 ImagesCat. No.: HY-185984a12k4E-Ca is a C-terminal glutamate-modified peptidogenic ionizable lipid that can be used for the preparation of lipid nanoparticles (LNPs). a12k4E-Ca preferentially accumulates in the spleen in vivo, acts as a carrier to mediate spleen-selective mRNA delivery, and enables spleen-specific Cre recombinase-mediated gene editing. a12k4E-Ca restores serum biochemical parameters and cytokines/chemokines. a12k4E-Ca can be used in studies related to LNP preparation.
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Cardiolipin (16:1/16:1/16:1/16:1) sodium salt
0 ImagesCat. No.: HY-157657CAS No.: 2260669-34-7Synonyms: Diphosphatidylglycerol sodium salt; 16:1 Cardiolipin sodium salt; 64:4-CL sodium saltCardiolipin (16:1/16:1/16:1/16:1) sodium salt is an anionic phospholipid that promote hydroxyapatite crystallization and supersaturation in a calcium solution.
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DSPC-d74
0 ImagesSynonyms: 1,2-Distearoyl-sn-glycero-3-PC-d74; 1,2-Distearoyl-sn-glycero-3-phosphorylcholine-d74DSPC-d74 (1,2-Distearoyl-sn-glycero-3-phosphorylcholine-d74) is the deuterium labeled DSPC (HY-W040193). DSPC is a cylindrical-shaped lipid. 1,2-Distearoyl-sn-glycero-3-phosphorylcholine is used to synthesize liposomes, and is the lipid component in the lipid nanoparticle (LNP) system.
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F-L319
0 ImagesCat. No.: HY-185760F-L319 is an ionizable lipid and spleen-targeting mRNA delivery vector. F-L319 can be formulated into lipid nanoparticles (LNPs) to drive spleen-restricted reporter protein expression in mice. F-L319 modulates mRNA encapsulation efficiency, cellular uptake efficiency, and delivery efficiency, with effects varying depending on the composition of LNP formulations. When prepared as pure LNPs, F-L319 shows poor mRNA delivery efficiency in cells; in contrast, hybrid LNPs containing F-L319 and L319 significantly enhance mRNA delivery efficiency in cells.
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diC8PI(3,5)P2 triammonium
0 ImagesCat. No.: HY-157713CAS No.: 852043-36-8Synonyms: 08:0 PI(3,5)P2 triammoniumdiC8PI(3,5)P2 (08:0 PI(3,5)P2) triammonium is a lipid that can be used to prepare lipid nanoparticles (LNPs) for drug delivery.
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1-1(Z)-Octadecenyl-2-adrenoyl-sn-glycero-3-PC
0 ImagesCat. No.: HY-1751131-1(Z)-Octadecenyl-2-adrenoyl-sn-glycero-3-PC is a plasmalogen that contains 1(Z)-octadecenoic acid and adrenic acid (HY-W013215) at the sn-1 and sn-2 positions, respectively.
