Liposome
Liposomes (NPs typically 100–500 nm in diameter) are fabricated from the self-assembly of phospholipids, which consist of a polar phosphate head group and hydrophobic lipid tails. In aqueous environments, the hydrophobic tails self-orient, resulting in a spherical structure comprised of an aqueous core surrounded by a lipophilic bilayer membrane. Liposomes are both biocompatible and biodegradable (e.g., at certain pH and temperature), which can be controlled by modifying the lipid composition. Furthermore, liposomes are amenable to various modifications that improve their efficacy as drug delivery carriers.
All Product Categories
-
Liposome Related Products (1030)
Related Products (1030)
-
((1-Hydroxybutan-2-yl)azanediyl)bis(hexane-6,1-diyl) bis(2-hexyldecanoate)
0 ImagesCat. No.: HY-W1130405CAS No.: 2036273-20-6((1-Hydroxybutan-2-yl)azanediyl)bis(hexane-6,1-diyl) bis(2-hexyldecanoate) is an ionizable cationic lipid (pKa = 4.67) and a derivative of ALC-0315).
-
ATX-012
0 ImagesCat. No.: HY-183001CAS No.: 1777792-44-5
-
a12Dab4
0 ImagesCat. No.: HY-185977CAS No.: 3113145-01-7a12Dab4 is a peptide ionizable lipid (PIL) used in lipid nanoparticle (LNP) formulations for targeted delivery of mRNA to the liver.
-
mPEG2000-DCG
0 ImagesCat. No.: HY-179910CAS No.: 1566560-80-2mPEG2000-DCG is a PEG-based lipid that can be used to formulate lipid nanoparticles for drug delivery.
-
DMPE-PEG5000 ammonium
0 ImagesCat. No.: HY-155929CAS No.: 474922-82-2Synonyms: 14:0 PEG5000 PE ammonium; 1,2-Dimyristoyl-sn-glycero-3-phosphoethanolamine-N-[methoxy(polyethylene glycol)-5000] ammoniumDMPE-PEG5000 ammonium (14:0 PEG5000 PE ammonium) is a PEG lipid functional end group used in the synthesis of liposomes (LPs) for the design of conjugated polymer nanoparticles. Through biotin modification and carboxyl terminus, lipid nanoparticles (LNPs) further coupling with other biomolecules can be achieved. Functionalized nanoparticles can be used for targeted labeling of specific cellular proteins. With streptavidin as a linker, biotinylated PEG lipid-conjugated polymer nanoparticles are able to bind to biotinylated antibodies on cell surface receptors, yielding the utility of fluorescence-based imaging and sensing.
-
22:6 PG sodium
0 ImagesCat. No.: HY-157691CAS No.: 474943-23-222:6 PG sodium is a lipid that can be used to prepare lipid nanoparticles (LNPs) for drug delivery.
-
DOPE-C8
0 ImagesCat. No.: HY-175410CAS No.: 3081750-70-8Synonyms: 1,2-Dioloeoyl-sn-glycero-3-phosphoethanolamine-C8; 1,2-DOPE-C8DOPE-C8 (1,2-Dioloeoyl-sn-glycero-3-phosphoethanolamine-C8; 1,2-DOPE-C8) is a zwitterionic phospholipid derived from DOPE that has been used to generate lipid nanoparticles (LNPs) for in vivo delivery of mRNA.
-
DPPE-mPEG sodium
0 ImagesCat. No.: HY-179837CAS No.: 384835-61-4DPPE-mPEG sodium is a lipid that can be used to prepare lipid nanoparticles (LNPs) for drug delivery.
-
1,2-Dilinolenoyl-sn-Glycero-3-Phosphatidylcholine
0 ImagesCat. No.: HY-N16165CAS No.: 40811-59-4Synonyms: 18:3 PC; Dilinolenoylphosphatidylcholine1,2-Dilinolenoyl-sn-Glycero-3-Phosphatidylcholine (18:3 PC; Dilinolenoylphosphatidylcholine) is a phosphatidylcholine derivative and zwitterionic phospholipid. 1,2-Dilinolenoyl-sn-Glycero-3-Phosphatidylcholine serves as a component of oral liposomal compositions.
-
DPPC-13C
0 ImagesCat. No.: HY-109506S10Synonyms: 129Y83-13CDPPC-13C3 (129Y83-13C) is the 13C-labeled DPPC (HY-109506). DPPC (129Y83) is a phosphoglyceride that can be used to prepare lipid monolayers, bilayers, and liposomes. DPPC is the main lipid component of pulmonary surfactant. Dppc-liposome can be effectively used as a delivery vector to induce an immune response against GSL antigen in mice.
