Liposome
Liposomes (NPs typically 100–500 nm in diameter) are fabricated from the self-assembly of phospholipids, which consist of a polar phosphate head group and hydrophobic lipid tails. In aqueous environments, the hydrophobic tails self-orient, resulting in a spherical structure comprised of an aqueous core surrounded by a lipophilic bilayer membrane. Liposomes are both biocompatible and biodegradable (e.g., at certain pH and temperature), which can be controlled by modifying the lipid composition. Furthermore, liposomes are amenable to various modifications that improve their efficacy as drug delivery carriers.
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Liposome Related Products (1037)
Related Products (1037)
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SAINT-2
0 ImagesCat. No.: HY-158705CAS No.: 187587-97-9SAINT-2 is a cationic lipid with gene transfection activity and is a pyridyl lipid analog. Molecular membranes prepared by SAINT-2 can interact with plasmids to form lipid complexes. After the complex is taken up by cells, the plasmid dissociates from the lipid complex under the action of DOPE and the plasmid translocates across the endosome and/or nuclear membrane. Thus, SAINT-2 effectively transfers small oligonucleotides into cells.
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Stearic acid-PEG5000-Rhodamine
0 ImagesCat. No.: HY-W440936Stearic acid-PEG5000-Rhodamine is a fatty acid containing PEG polymer which can self assemble in an aqueous solution to form micelles. The polymer can be used to prepare nanoparticles for drug encapsulation. The red dye rhodamine can be easily traced by fluorescence microscopy. Rhodamine has maximum absorption at 570 nm and emission around 595 nm.
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Stearic acid-PEG2000-Rhodamine
0 ImagesCat. No.: HY-W440934Stearic acid-PEG2000-Rhodamine is an amphiphilic PEG polymer which can form micelles in water. The rhodamine can be used for staining sample and easily traced by fluorescence microscopy. Rhodamine has maximum absorption at 570 nm and emission around 595 nm.
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G0-C14 analog
0 ImagesCat. No.: HY-159869CAS No.: 2935435-86-0G0-C14 analog is a G0-C14 derivative. G0-C14 is an ionizable cationic lipid that can be used to synthesize lipid nanoparticles (LNP).
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1-Stearoyl-2-17(S)-HDoTE-sn-glycero-3-PE
0 ImagesCat. No.: HY-1751151-Stearoyl-2-17(S)-HDoTE-sn-glycero-3-PE is a phospholipid. 1-Stearoyl-2-17(S)-HDoTE-sn-glycero-3-PE contains Stearic acid (HY-B2219) and the oxidized adrenic acid metabolite 17(S)-HDoTE (HY-168774) at the sn-1 and sn-2 positions, respectively.
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NH2-GG-DSPE
0 ImagesCat. No.: HY-164579CAS No.: 1364335-16-9NH2-GG-DSPE is a lipid compound that can be used for liposome preparation. Liposomes are the main component of vesicles with concentric phospholipid bilayer membranes, which can be used to construct drug delivery systems for anti-cancer and anti-infection fields. Highly polar water-soluble loads can be captured in the internal aqueous space of liposomes, while lipophilic loads can be distributed into the lipid bilayer and become part of the lipid bilayer. Especially for the delivery of antisense oligonucleotides, it can overcome the problems of inefficient cellular uptake and rapid loss in the body.
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DMPE-PEG550 ammonium
0 ImagesCat. No.: HY-155925CAS No.: 474922-82-2Synonyms: 14:0 PEG550 PE ammonium; 1,2-Dimyristoyl-sn-glycero-3-phosphoethanolamine-N-[methoxy(polyethylene glycol)-550] ammoniumDMPE-PEG550 ammonium (14:0 PEG550 PE ammonium) is a PEG lipid functional end group used in the synthesis of liposomes (LPs) for the design of conjugated polymeric nanoparticles. Through biotin modification and carboxyl terminus, lipid nanoparticles (LNPs) further coupling with other biomolecules can be achieved. Functionalized nanoparticles can be used for targeted labeling of specific cellular proteins. With streptavidin as a linker, biotinylated PEG lipid-conjugated polymer nanoparticles are able to bind to biotinylated antibodies on cell surface receptors, yielding the utility of fluorescence-based imaging and sensing.
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C16 LPA ammonium
0 ImagesCat. No.: HY-W725317CAS No.: 799279-66-6Synonyms: PA(16:0e/0:0) ammoniumC16 LPA (PA(16:0e/0:0)) ammonium is a lipid that can be used to prepare lipid nanoparticles (LNPs) for drug delivery.
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LNP Lipid-6
0 ImagesCat. No.: HY-153376CAS No.: 2226547-32-4LNP Lipid-6 (Compound Lipid 5) is an ionizable lipid (amino lipid). LNP Lipid-6 can be used to prepare lipid nanoparticles (LNP).
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DC-6-14
0 ImagesCat. No.: HY-W800782CAS No.: 107086-76-0DC-6-14 is a cationic lipid with gene transfection activity, which can be used for the synthesis of liposomes.
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DSPE-PEG5000-Cy5
0 ImagesCat. No.: HY-W440913DSPE-PEG5000-Cy5 is a fluorescently labeled PEGylated phospholipid. After intravenous injection, DSPE-PEG5000-Cy5 shows only extremely low fluorescence accumulation at tumor sites in orthotopic tumor-bearing mice, and can be used as a negative control for evaluating tumor accumulation of nanoparticles. DSPE-PEG5000-Cy5 can serve as a fluorescent marker to prepare Cy5-labeled NPs-DPPA and NPs-DPPA (C3F8) for pharmacokinetic and biodistribution studies in mice. DSPE-PEG5000-Cy5 is widely applicable to research in fields related to triple-negative breast cancer, hepatocellular carcinoma and so on.
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Stearic acid-PEG3400-Rhodamine
0 ImagesCat. No.: HY-W440935Stearic acid-PEG3400-Rhodamine is a fatty acid containing PEG polymer which can self assemble in an aqueous solution to form micelles. The polymer can be used to prepare nanoparticles for drug encapsulation. The red dye rhodamine can be easily traced by fluorescence microscopy. Rhodamine has maximum absorption at 570 nm and emission around 595 nm.
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MeDZ lipid
0 ImagesCat. No.: HY-185284MeDZ lipid is a zwitterion-type ionizable endosomal membrane destabilizer and anti-inflammatory agent that promotes endosomal escape. When incorporated into LNP formulations, MeDZ lipid enhances mRNA expression in lymph node antigen-presenting cells and promotes cytotoxic T cell activation. MeDZ lipid is compatible with existing targeted nanoparticle formulations to improve mRNA delivery efficiency.
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Lipid M
0 ImagesCat. No.: HY-132289CAS No.: 2089251-57-8Lipid M (pKa: 6.75) can be used to deliver mRNA vaccine and yield a robust immune response with improved tolerability.
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L-Arg-DSPE
0 ImagesCat. No.: HY-182988CAS No.: 2681258-65-9L-Arg-DSPE is an arginine-functionalized DSPE lipid containing free guanidine groups. L-Arg-DSPE serves as a component of NO-responsive degradable drug-loaded liposomal nanomotors (L-Arg@Lip-DOX), promoting drug deep tumor tissue penetration and cellular internalization. L-Arg-DSPE can be used for the research of drug delivery.
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3β-[N-(N′,N′-Dimethylaminoethyl)carbamoyl]cholesterol
![3β-[N-(N′,N′-Dimethylaminoethyl)carbamoyl]cholesterol](https://file.medchemexpress.com/product_pic/hy-149664.gif "Click to View 3β-[N-(N′,N′-Dimethylaminoethyl)carbamoyl]cholesterol Product Detail")
0 ImagesCat. No.: HY-149664CAS No.: 137056-72-5Synonyms: DC-Chol3β-[N-(N′,N′-Dimethylaminoethyl)carbamoyl]cholesterol, a lipid, has been investigated in cancer gene therapy and vaccine delivery system.
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DSPE-PEG3400-Cy5
0 ImagesCat. No.: HY-W440912DSPE-PEG3400-Cy5 is a PEG phospholipid with Cy5 dye used in protein/nucelic acid labeling and fluorescence microscopy. The polymer can self-assemble in aqueous solution to form micelles/lipid bilayer and used to prepare liposomes or nanoparticles for nutrients delivery such as mRNA or DNA vaccine.
