Liposome
Liposomes (NPs typically 100–500 nm in diameter) are fabricated from the self-assembly of phospholipids, which consist of a polar phosphate head group and hydrophobic lipid tails. In aqueous environments, the hydrophobic tails self-orient, resulting in a spherical structure comprised of an aqueous core surrounded by a lipophilic bilayer membrane. Liposomes are both biocompatible and biodegradable (e.g., at certain pH and temperature), which can be controlled by modifying the lipid composition. Furthermore, liposomes are amenable to various modifications that improve their efficacy as drug delivery carriers.
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Liposome Related Products (1038)
Related Products (1038)
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DSPE-PEG10000-OH
0 ImagesCat. No.: HY-164723DSPE-PEG10000-OH is a hydroxy-terminated phospholipid PEG polymer. The hydrophobic tails that allows the encapsulation and aggregation of other hydrophobic drugs, and the hydroxy-terminated can be further reacted. DSPE-PEG10000-OH can prepare liposomes or lipid nanoparticles, which can be used in drug delivery and promoting drug absorption research.
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Lipid R6
0 ImagesCat. No.: HY-159713CAS No.: 3063868-61-8Lipid R6 is a lipid molecule that can be used to synthesize liposomes and is the lipid component in lipid nanoparticle (LNP) systems.
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Bis(bis(2-carboxyethyl)aminopropyl)methylamine
0 ImagesCat. No.: HY-W440820CAS No.: 692250-70-7Bis(bis(2-carboxyethyl)aminopropyl)methylamine is a symmetrical branched linker featuring three tertiary amines and four carboxylic acids. Each carboxylic acid is open to forming esters or amides. It can be used in developing lipid nanoparticles.
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LNP Lipid II-10
0 ImagesCat. No.: HY-173295CAS No.: 2036272-60-1LNP Lipid II-10 can be used in the development of lipid nanoparticles (LNPs).
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DPPE-MPEG (2000)
0 ImagesCat. No.: HY-165156CAS No.: 459429-07-3Synonyms: 1,2-DPPE-MPEG(2000)DPPE-MPEG 2000 (1,2-DPPE-MPEG(2000)) is a PEG-modified lipids. DPPE-MPEG 2000 can reduce the nonspecific adsorption of protein and prolong circulation time in vivo.
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1,2-DLPC (Standard)
0 ImagesCat. No.: HY-107737RCAS No.: 18194-25-7Synonyms: 1,2-Dilauroyl-sn-glycero-3-phosphocholine (Standard)1,2-DLPC (Standard) is the analytical standard of 1,2-DLPC (HY-107737). This product is intended for research and analytical applications. 1,2-DLPC (1,2-Dilauroyl-sn-glycero-3-phosphocholine) is a ligand for LRH-1 agonists. 1,2-DLPC is a phospholipid used in the synthesis of liposomes. 1,2-DLPC enhances fat breaKdown and apoptosis in fat cells through a TNFα-dependent pathway, while also inhibiting palmitate-induced insulin resistance through PPARα-mediated inflammation in muscle cells.
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DSPE-PEG6000-OH
0 ImagesCat. No.: HY-164721DSPE-PEG6000-OH is a hydroxy-terminated phospholipid PEG polymer. The hydrophobic tails that allows the encapsulation and aggregation of other hydrophobic drugs, and the hydroxy-terminated can be further reacted. DSPE-PEG6000-OH can prepare liposomes or lipid nanoparticles, which can be used in drug delivery and promoting drug absorption research.
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Bis(linoleyl) ketone
0 ImagesCat. No.: HY-W251490CAS No.: 1169768-30-2Bis(linoleyl) ketone is a lipid that can be used to prepare lipid nanoparticles (LNPs) for drug delivery.
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Oleoyl-Gly-Lys-(m-PEG11)-NH2
0 ImagesCat. No.: HY-W440807CAS No.: 2353409-68-2Oleoyl-Gly-Lys-(m-PEG11)-NH2 is a PEG-lipid molecule featuring an oleoyl amide linked to a Gly-Lys dipeptide and a methoxy PEG11 chain on the C-terminus of the lysine. The lysine primary amine may be used in a wide variety of reactions with carboxylic acids, NHS esters, and carbonyl groups. The PEG linker provides aqueous solubility.
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1,2-Dioleoyl-sn-glycero-3-PA ammonium salt
0 ImagesCat. No.: HY-175069Synonyms: PA(18:1/18:1) ammonium salt; 1,2-DOPA ammonium salt1,2-Dioleoyl-sn-glycero-3-PA (ammonium salt) is a phospholipid with long-chain fatty acid oleic acid inserted at the sn-1 and sn-2 positions. 1,2-Dioleoyl-sn-glycero-3-PA (ammonium salt) can be used to synthsize artificial membranes such as liposomes.
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DLin-C-DAP
0 ImagesCat. No.: HY-179828CAS No.: 1169768-13-1DLin-C-DAP is a cationic lipid that can be used to prepare lipid nanoparticles (LNPs) for drug delivery.
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DMDHP
0 ImagesCat. No.: HY-17650CAS No.: 189743-89-3Synonyms: (±)-Dimyristoyl-2,3-dimethylhydroxypropylamineDMDHP ((±)-Dimyristoyl-2,3-dimethylhydroxypropylamine) is a cationic lipid with a polar head group containing a dihydroxy group. DMDHP exhibits superior transfection efficiency and lower toxicity at high DNA doses in mouse intrapulmonary transfection model. DMDHP is commonly used for gene delivery.
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16:0 SB (DPSB)
0 ImagesCat. No.: HY-N15938CAS No.: 1352945-49-316:0 SB (DPSB) is a fixed cationic lipid.
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(S)-1,2-Dipalmitoyl-sn-glycero-3-phosphoethanolamine
0 ImagesCat. No.: HY-184404CAS No.: 71357-99-8(S)-1,2-Dipalmitoyl-sn-glycero-3-phosphoethanolamine is a phosphatidylethanolamine lipid with palmitoyl fatty acid chains. (S)-1,2-Dipalmitoyl-sn-glycero-3-phosphoethanolamine serves as a substrate for glycosylation reactions and a component of biocompatible pH-sensitive hydrophobic copolymer nanoparticles. (S)-1,2-Dipalmitoyl-sn-glycero-3-phosphoethanolamine exhibits pH-sensitive drug release properties, enabling faster drug release in acidic environments. (S)-1,2-Dipalmitoyl-sn-glycero-3-phosphoethanolamine can be used in studies related to cancer drug delivery.
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(Rac)-SOPC
0 ImagesCat. No.: HY-W440982ACAS No.: 6753-56-6Synonyms: (Rac)-PC(18:0/18:1); (Rac)-2-Oleoyl-1-stearoyl-sn-glycero-3-phosphocholine(Rac)-SOPC ((Rac)-PC(18:0/18:1)) ((Rac)-2-Oleoyl-1-stearoyl-sn-glycero-3-phosphocholine) is the racemate of SOPC (HY-W440982). SOPC is an asymmetrical phospholipid with saturated fatty acid (stearic acid/18:0) at sn-1 position and unsaturated fatty acid (oleic acid/18:1) at sn-2 position. SOPC can stabilize the outer segment membrane of frog rods.
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Lipid 7-1
0 ImagesCat. No.: HY-168777CAS No.: 2795392-95-7Lipid 7-1 is an ionizable cationic lipid that can be used for the preparation of liposomes.
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IR-117-17
0 ImagesSynonyms: A10-LinIR-117-17 is an ionizable cationic amino lipid, targeting conducting airways of the lung. IR-117-17 could be degraded via esterase cleavage and thus be unlikely to accumulate upon repeated dosing. It can be used in research related to diseases that manifest outside alveolar spaces.
