18194-25-7
18194-25-7
Chemical Structure
1,2-DLPC
Synonym(s): 1,2-Dilauroyl-sn-glycero-3-phosphocholine
- CAS No.: 18194-25-7
- Formula:C32H64NO8P
- Molecular Weight:621.83
IUPAC Name: (R)-2,3-bis(dodecanoyloxy)propyl (2-(trimethylammonio)ethyl) phosphate
InChIKey: IJFVSSZAOYLHEE-SSEXGKCCSA-N
SMILES: CCCCCCCCCCCC(OC[C@@H](OC(CCCCCCCCCCC)=O)COP(OCC[N+](C)(C)C)([O-])=O)=O
Biological Activity: 1,2-DLPC (1,2-Dilauroyl-sn-glycero-3-phosphocholine) is a ligand for LRH-1 agonists. 1,2-DLPC is a phospholipid used in the synthesis of liposomes. 1,2-DLPC enhances fat breakdown and apoptosis in fat cells through a TNFα-dependent pathway, while also inhibiting palmitate-induced insulin resistance through PPARα-mediated inflammation in muscle cells[1][2][3].
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1,2-DLPC | 98.0% | 1,2-DLPC (1,2-Dilauroyl-sn-glycero-3-phosphocholine) is a ligand for LRH-1 agonists. 1,2-DLPC is a phospholipid used in the synthesis of liposomes. 1,2-DLPC enhances fat breakdown and apoptosis in fat cells through a TNFα-dependent pathway, while also inhibiting palmitate-induced insulin resistance through PPARα-mediated inflammation in muscle cells. | ||||||||||||||||||||
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1,2-DLPC (Standard) | ≥98% | 1,2-DLPC (Standard) is the analytical standard of 1,2-DLPC (HY-107737). This product is intended for research and analytical applications. 1,2-DLPC (1,2-Dilauroyl-sn-glycero-3-phosphocholine) is a ligand for LRH-1 agonists. 1,2-DLPC is a phospholipid used in the synthesis of liposomes. 1,2-DLPC enhances fat breaKdown and apoptosis in fat cells through a TNFα-dependent pathway, while also inhibiting palmitate-induced insulin resistance through PPARα-mediated inflammation in muscle cells. | ||||||||||||||||||||
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1,2-DLPC-d9 | 1,2-DLPC-d9 (1,2-Dilauroyl-sn-glycero-3-phosphocholine-d9) is the deuterium labeled 1,2-DLPC. 1,2-DLPC (1,2-Dilauroyl-sn-glycero-3-phosphocholine) is a ligand for LRH-1 agonists. 1,2-DLPC is a phospholipid used in the synthesis of liposomes. 1,2-DLPC enhances fat breakdown and apoptosis in fat cells through a TNFα-dependent pathway, while also inhibiting palmitate-induced insulin resistance through PPARα-mediated inflammation in muscle cells. | |||||||||||||||||||||
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1,2-DLPC-d46 | 1,2-DLPC-d46 (1,2-Dilauroyl-sn-glycero-3-phosphocholine-d46) is the deuterium labeled 1,2-DLPC. 1,2-DLPC (1,2-Dilauroyl-sn-glycero-3-phosphocholine) is a ligand for LRH-1 agonists. 1,2-DLPC is a phospholipid used in the synthesis of liposomes. 1,2-DLPC enhances fat breakdown and apoptosis in fat cells through a TNFα-dependent pathway, while also inhibiting palmitate-induced insulin resistance through PPARα-mediated inflammation in muscle cells. | |||||||||||||||||||||
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1,2-DLPC-d55 | 1,2-DLPC-d55 (1,2-Dilauroyl-sn-glycero-3-phosphocholine-d55) is the deuterium labeled 1,2-DLPC. 1,2-DLPC (1,2-Dilauroyl-sn-glycero-3-phosphocholine) is a ligand for LRH-1 agonists. 1,2-DLPC is a phospholipid used in the synthesis of liposomes. 1,2-DLPC enhances fat breakdown and apoptosis in fat cells through a TNFα-dependent pathway, while also inhibiting palmitate-induced insulin resistance through PPARα-mediated inflammation in muscle cells. | |||||||||||||||||||||
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References
- [1]. Matthew E Nipper, et al. Detection of liposome membrane viscosity perturbations with ratiometric molecular rotors. Biochimie. 2011 Jun;93(6):988-94. [Content Brief]
- [2]. Jae Man Lee, et al. A nuclear-receptor-dependent phosphatidylcholine pathway with antidiabetic effects. Nature. 2011 May 25;474(7352):506-10. [Content Brief]
- [3]. Jinwoo Park, et al. 1,2-Dilinoleoyl-sn-glycero-3-phosphocholine increases insulin sensitivity in palmitate-treated myotubes and induces lipolysis in adipocytes. Biochem Biophys Res Commun. 2020 Nov 26;533(1):162-167. [Content Brief]
