71357-99-8
Chemical Structure
(S)-1,2-Dipalmitoyl-sn-glycero-3-phosphoethanolamine
- CAS No.: 71357-99-8
- Formula:C37H74NO8P
- Molecular Weight:691.97
IUPAC Name: (2S)-3-(((2-aminoethoxy)(hydroxy)phosphoryl)oxy)propane-1,2-diyl dipalmitate
InChIKey: SLKDGVPOSSLUAI-DHUJRADRSA-N
SMILES: [C@H](OC(CCCCCCCCCCCCCCC)=O)(COC(CCCCCCCCCCCCCCC)=O)COP(OCCN)(=O)O
Biological Activity: (S)-1,2-Dipalmitoyl-sn-glycero-3-phosphoethanolamine is a phosphatidylethanolamine lipid with palmitoyl fatty acid chains. (S)-1,2-Dipalmitoyl-sn-glycero-3-phosphoethanolamine serves as a substrate for glycosylation reactions and a component of biocompatible pH-sensitive hydrophobic copolymer nanoparticles. (S)-1,2-Dipalmitoyl-sn-glycero-3-phosphoethanolamine exhibits pH-sensitive drug release properties, enabling faster drug release in acidic environments. (S)-1,2-Dipalmitoyl-sn-glycero-3-phosphoethanolamine can be used in studies related to cancer drug delivery[1][2].
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(S)-1,2-Dipalmitoyl-sn-glycero-3-phosphoethanolamine | (S)-1,2-Dipalmitoyl-sn-glycero-3-phosphoethanolamine is a phosphatidylethanolamine lipid with palmitoyl fatty acid chains. (S)-1,2-Dipalmitoyl-sn-glycero-3-phosphoethanolamine serves as a substrate for glycosylation reactions and a component of biocompatible pH-sensitive hydrophobic copolymer nanoparticles. (S)-1,2-Dipalmitoyl-sn-glycero-3-phosphoethanolamine exhibits pH-sensitive drug release properties, enabling faster drug release in acidic environments. (S)-1,2-Dipalmitoyl-sn-glycero-3-phosphoethanolamine can be used in studies related to cancer drug delivery. | |||||||||||||||||||||
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- [1]. Lin Q, et al. A preliminary study on the formation pathways of glycated phosphatidylethanolamine of food rich in phospholipid during the heat-processing. RSC advances. 2018 Mar 21;8(21):11280-11288. [Content Brief]
- [2]. Wu Y, et al. Construction of amphiphilic copolymer nanoparticles based on hyperbranched poly (amine-ester) and 1,2-dipalmitoyl-sn-glycero-3-phosphoethanolamine as drug carriers for cancer therapy. Nanomedicine : nanotechnology, biology, and medicine. 2011 Dec;7(6):945-54. [Content Brief]
