Liposome
Liposomes (NPs typically 100–500 nm in diameter) are fabricated from the self-assembly of phospholipids, which consist of a polar phosphate head group and hydrophobic lipid tails. In aqueous environments, the hydrophobic tails self-orient, resulting in a spherical structure comprised of an aqueous core surrounded by a lipophilic bilayer membrane. Liposomes are both biocompatible and biodegradable (e.g., at certain pH and temperature), which can be controlled by modifying the lipid composition. Furthermore, liposomes are amenable to various modifications that improve their efficacy as drug delivery carriers.
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Liposome Related Products (1037)
Related Products (1037)
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DSPE-PEG5000-Fluor 488
0 ImagesCat. No.: HY-160270DSPE-PEG5000-Fluor 488 is a PEG-dye-lipid conjugate consists of a DSPE phospholipid which is an unsaturated phospholipid, a Fluor 488 dye which is a cyanine dye that is prominently used in fluorescence microscopy with excitation and emission maxima at 499 nm and 520 nm and a large PEG spacer which links the former substance together.
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1,2-Dipalmitoyl-sn-glycero-3-PS
0 ImagesCat. No.: HY-145539ACAS No.: 40290-42-41,2-Dipalmitoyl-sn-glycero-3-PS is a phosphatidylserine phospholipid. 1,2-Dipalmitoyl-sn-glycero-3-PS is used for the preparation of phospholipid bilayers.
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A-066
0 ImagesCat. No.: HY-185223CAS No.: 1192362-77-8A-066 (Formula I) is a cationic lipid. A-066 forms Cationic-Based Lipid Encapsulation Systems (CaBLES) or Lipid-Based Particles. A-066 facilitates delivery of nucleic acids and other agents.
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6-Bromohexyl 2-hexyldecanoate
0 ImagesCat. No.: HY-W440811CAS No.: 2644752-91-86-Bromohexyl 2-hexyldecanoate is a lipid. 6-Bromohexyl 2-hexyldecanoate can be used to build lipid nanoparticles and nanomaterials.
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DSPE-PEG3400-Cy3
0 ImagesCat. No.: HY-W440909DSPE-PEG3400-Cy3 is a phospholipid PEG polymer with Cy3 dye used in labeling and fluorescence microscopy. The polymer can self-assemble in aqueous solution to form micelles/lipid bilayer and used to prepare liposomes or nanoparticles for nutrients delivery such as mRNA or DNA vaccine.
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DOSPA (hydrochlorid)
0 ImagesCat. No.: HY-158867CAS No.: 913194-16-8DOSPA hydrochlorid is a frequently utilized cationic lipid in the generation of Lipid Nanoparticles (LNPs) for the development of mRNA vaccines, including the COVID-19 vaccine.
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nor-MC3
0 ImagesCat. No.: HY-185010CAS No.: 2870681-06-2nor-MC3 is an MC3-type ionizable lipid with C17 unsaturated chains, formulated in lipid nanoparticles for nucleic acid (mRNA and siRNA) delivery and supports in vitro and in vivo transfection.
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08:0 PG sodium
0 ImagesCat. No.: HY-157711CAS No.: 322647-21-208:0 PG sodium is a lipid that can be used to prepare lipid nanoparticles (LNPs) for drug delivery.
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10A1P16
0 ImagesCat. No.: HY-185751CAS No.: 2760467-77-210A1P16 is an ionizable phospholipid composed of a tertiary amine, a phosphate group and three hydrophobic tails. As a spleen-selective RNA delivery vector, 10A1P16 successfully transfects approximately 30% of splenic macrophages and 6% of splenic B cells in vivo. 10A1P16 can be used to prepare spleen-selective 10A1P16-MDOA lipid nanoparticles, which effectively mediate mRNA delivery and gene editing in mouse models. This delivery system retains potent spleen-targeted mRNA delivery efficacy and can be applied to ovarian cancer research.
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18:0-20:4 PI (3,5) P2 triammonium
0 ImagesCat. No.: HY-157649CAS No.: 799268-58-918:0-20:4 PI (3,5) P2 triammonium is a lipid that can be used to prepare lipid nanoparticles (LNPs) for drug delivery.
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CL15H6
0 ImagesCat. No.: HY-173245CAS No.: 2256087-40-6CL15H6 is an ionizable lipid featuring biodegradable ester linkages and oleic acid lipid tails.
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IR-19-Py
0 ImagesCat. No.: HY-185759CAS No.: 2940240-84-4IR-19-Py is an ionizable lipid suitable for aerosolized mRNA delivery. When formulated into lipid nanoparticles, IR-19-Py delivers mRNA to nasal tissues in mice, achieving sustained nasal protein expression and dose-dependent pulmonary protein expression. IR-19-Py can be used in cystic fibrosis research.
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1,2-Dilauroyl-sn-glycero-3-phosphate sodium
0 ImagesCat. No.: HY-113925CAS No.: 108321-06-8Synonyms: 1,2-DLPA Sodium; (2R)-2,3-bis(dodecanoyloxy)propyl hydrogen phosphate sodium1,2-Dilauroyl-sn-glycero-3-phosphate (1,2-DLPA) sodium is a phospholipid containing the medium-chain (12:0) lauric acid inserted at the sn-1 and sn-2 positions. It can be used in the generation of micelles, liposomes, and other types of artificial membranes.
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C14-306
0 ImagesCat. No.: HY-184363CAS No.: 2153563-36-9C14-306 is an ionizable lipid with a linear 306 amine core and a C14 alkyl tail. C14-306 enhances brain transfection efficiency. Lipid nanoparticles (LNP) formulated with C14-306 promote mRNA delivery, increase neuronal transfection rate, and facilitate Cre-mediated recombination in the brain, while reducing off-target expression in the liver.
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Decitabine-Cisplatin Liposome
0 ImagesCat. No.: HY-188004Decitabine-Cisplatin Liposome is a delivery system that encapsulates Decitabine (HY-A0004) and Cisplatin (HY-17394) within tiny liposomes. The liposomes act as a protective layer, enhancing the absorption and bioavailability of both Decitabine and Cisplatin. The combination of Decitabine and Cisplatin synergistically induces Sox2 DNA demethylation and promotes Sox2 gene expression, making it a useful tool for gastric cancer research.
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LP293-p
0 ImagesCat. No.: HY-180474CAS No.: 3024403-65-1LP293-p is a lipid with activated ester groups, which can be used for the synthesis of ATXN2 RNAi. LP293-p can be utilized to enhance the targeting of the central nervous system (CNS).
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DOPE-PEG-Azide ammonium
0 ImagesCat. No.: HY-179836CAS No.: 2342575-84-0DOPE-PEG-Azide ammonium is a lipid that can be used to prepare lipid nanoparticles (LNPs) for drug delivery.
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mPEG2000-DMPE sodium
0 ImagesCat. No.: HY-W1052192DCAS No.: 384835-59-0mPEG2000-DMPE sodium is a PEGylated 1,2-Dimyristoyl-sn-glycero-3-phosphoethanolamine (14:0 PE) compound with a methyl group at the other end of the PEG chain. The PEG polymer exhibits amphiphatic behavior and helps to form stable micelles in an aqueous solution. It can be used to prepare nanoparticles or liposomes for targeted drug delivery applications.
