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  5. GITR Antibody (YA1333)

GITR Antibody (YA1333) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to GITR.

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사이즈 재고
50 μL   견적 받기  
100 μL   견적 받기  

* 장바구니에 담기 전 물품의 수량을 선택해 주십시오.

Top Publications Citing Use of Products
  • WB: Western Blot;
  • IHC-P: Immunohistochemistry-Paraffin;
  • IHC-F: Immunohistochemistry-Frozen;
  • ICC/IF: Immunocytochemistry/Immunofluorescence;
  • IF-Tissue: Immunofluorescence-Tissue;
  • mIHC: Multiplex Immunohistochemical;
  • IP: Immunoprecipitation;
  • ChIP: Chromatin Immunoprecipitation;
  • FC: Flow Cytometry;
  • ELISA: Enzyme Linked Immunosorbent Assay

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  • 제품 설명

제품 설명

GITR Antibody (YA1333) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to GITR.
Host

Rabbit
Clonality

Recombinant, Monoclonal
분자량
Predicted band size: 26 kDa;
Observed band size: 26 kDa
Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.
Species Reactivity
Human
SwissProt ID
Gene ID
Immunogen

Recombinant human GITR protein
Application &
Dilution Ratio
Application Dilution Ratio
FC
FC: Flow Cytometry
1:50-1:100
ELISA
ELISA: Enzyme Linked Immunosorbent Assay
1:10000
Sensitivity Endogenous Purity Affinity Chromatography
Conjugation Non-conjugated Modification Unmodified
Isotype IgG  
Appearance

Liquid
Formulation

Supplied in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.
Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
선적

Shipping with blue ice.
Background
Function：Receptor for TNFSF18. Seems to be involved in interactions between activated T-lymphocytes and endothelial cells and in the regulation of T-cell receptor-mediated cell death. Mediated NF-kappa-B activation via the TRAF2/NIK pathway
Subcellular Localization：Cell membrane; Single-pass type I membrane protein; Secreted
Expression：
Tissue_specificity:It is expressed in lymph nodes and peripheral blood leukocytes, but its expression is weaker in the spleen.

Induction:Up-regulated in peripherical mononuclear cells after antigen stimulation/lymphocyte activation
Isoforms & Post-Translational Modification：Q9Y5U5 has 3 isomers: Q9Y5U5-1: 26000 Da (predicted); Q9Y5U5-2: 26827 Da (predicted); Q9Y5U5-3: 25110 Da (predicted).
Subunit：Binds to TRAF1, TRAF2, and TRAF3, but not TRAF5 and TRAF6. Binds through its C-terminus to SIVA1/SIVA
Database

Entrez Gene: 8784 Human

SwissProt: Q9Y5U5 Human

OMIM: 603905 Human

Research Field

Signal Transduction
Synonyms
AITR; GITR; TNFRSF18; CD357
각종 서류
User Guide for Antibodies (1077 KB)

GITR Antibody (YA1333) Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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상품명:
GITR Antibody (YA1333)
Cat. No.:
HY-P81588
수량:
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