(1R,2S)-NCD38 TFA
(1R,2S)-NCD38 TFA is an enantiomer of NCD38 TFA. NCD38 TFA is a LSD1-selective inhibitor.
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- CAS. Nr.: 2078047-42-2
- Formel: C37H37ClF3N3O4
- Molecular Weight:680.16
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Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biologische Aktivität
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Chemical Information
- Reinheit & Dokumentation
- Verweise
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Help & FAQs
Biologische Aktivität
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| A549 | GI50 |
8.6 μM
Compound: NCD38
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Growth inhibition of human A549 cells after 72 hrs by Alamarblue assay
Growth inhibition of human A549 cells after 72 hrs by Alamarblue assay
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[PMID: 29331452] |
Chemical Information
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CAS. Nr. 2078047-42-2
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Molecular Weight 680.16
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Formel C37H37ClF3N3O4
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SMILES
O=C(C1=CC=C(C2=CC=CC=C2)C=C1)N[C@H](C(NCC3=CC=CC(Cl)=C3)=O)CCCCN[C@H]4[C@H](C5=CC=CC=C5)C4.O=C(O)C(F)(F)F
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Reinheit & Dokumentation
Verweise
[1]. G R Sareddy, et al. Novel KDM1A inhibitors induce differentiation and apoptosis of glioma stem cells via unfolded protein response pathway. Oncogene. 2017 Apr 27;36(17):2423-2434. [Content Brief]
[2]. Yosuke Ota , et al. Design, synthesis and evaluation of γ-turn mimetics as LSD1-selective inhibitors. Bioorg Med Chem. 2018 Feb 1;26(3):775-785. [Content Brief]
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
(1R,2S)-NCD38 TFA Related Classifications
HY-112304A Related Classifications
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