2078047-42-2
2078047-42-2
Chemical Structure
(1R,2S)-NCD38 TFA
- CAS No.: 2078047-42-2
- Formula:C37H37ClF3N3O4
- Molecular Weight:680.16
InChIKey: SCYPMEPRSQTTPW-WBAULYFBSA-N
SMILES: O=C(C1=CC=C(C2=CC=CC=C2)C=C1)N[C@H](C(NCC3=CC=CC(Cl)=C3)=O)CCCCN[C@H]4[C@H](C5=CC=CC=C5)C4.O=C(O)C(F)(F)F
Biological Activity: (1R,2S)-NCD38 TFA is an enantiomer of NCD38 TFA. NCD38 TFA is a LSD1-selective inhibitor[1][2].
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(1R,2S)-NCD38 TFA | (1R,2S)-NCD38 TFA is an enantiomer of NCD38 TFA. NCD38 TFA is a LSD1-selective inhibitor. | |||||||||||||||||||||
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References
- [1]. G R Sareddy, et al. Novel KDM1A inhibitors induce differentiation and apoptosis of glioma stem cells via unfolded protein response pathway. Oncogene. 2017 Apr 27;36(17):2423-2434. [Content Brief]
- [2]. Yosuke Ota , et al. Design, synthesis and evaluation of γ-turn mimetics as LSD1-selective inhibitors. Bioorg Med Chem. 2018 Feb 1;26(3):775-785. [Content Brief]
