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Art. -Nr.: HY-122150

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AMPA receptor modulator-3

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AMPA receptor modulator-3 is an allosteric AMPA receptor modulator (EC₅₀: 4.4 μM). AMPA receptor modulator-3 can be used in the research of mammalian nervous system, such as learning and memory.

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Reinheit: 99.57%
CAS. Nr.: 211311-39-6
Formel: C₁₈H₂₂FNO₂S
Molecular Weight:335.44

Speicherung:

Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month

AMPA receptor modulator-3 Chemical Structure

CAS. Nr.: 211311-39-6

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Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biologische Aktivität
- Beschreibung
- Cellular Effect
- In Vitro
Chemical Information
Lösungsmittel & Löslichkeit
- In Vitro
Reinheit & Dokumentation
Verweise
Help & FAQs
Classifications
Bioz

Biologische Aktivität

Beschreibung

Alle iGluR Isoform-spezifische Produkte anzeigen :

Cellular Effect

Cell Line	Type	Value	Description	References
HEK293	EC₅₀	4.4 μM Compound: 5e	Tested for potentiation towards human iGluR4 receptor expressed in HEK293 cells Tested for potentiation towards human iGluR4 receptor expressed in HEK293 cells	[PMID: 11087558]

In Vitro

AMPA receptor modulator-3 (Compound 5e) shows an EC₅₀ value of 4.4 μM for potentiation of responses mediated by 100 μM L-glutamate in HEK-293 cells expressing iGluR4 flip^[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS. Nr. 211311-39-6
Appearance Solid
Molecular Weight 335.44
Formel C₁₈H₂₂FNO₂S
Color White to off-white
SMILES

CC(S(=O)(NCC(C1=CC=C(C2=CC=CC=C2F)C=C1)C)=O)C
Versand

Room temperature in continental US; may vary elsewhere.

Speicherung

Powder	-20°C	3 years
	4°C	2 years
In solvent	-80°C	6 months
	-20°C	1 month

Lösungsmittel & Löslichkeit

In Vitro:

DMSO : 250 mg/mL (745.29 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

View the Complete Stock Solution Preparation Table

Preparing Stock Solutions

View the Complete Stock Solution Preparation Table

Concentration Solvent Mass

1 mg

5 mg

10 mg

Concentration

Solvent

Mass

1 mM

2.9812 mL

14.9058 mL

29.8116 mL

5 mM

0.5962 mL

2.9812 mL

5.9623 mL

10 mM

0.2981 mL

1.4906 mL

2.9812 mL

Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.

Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Molaritätsrechner

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Konzentration Konzentration

Volumen Volumen

Molecular Weight Molecular Weight

Verdünnungsrechner

Konzentration _{(Stammlösung)} × Volumen _{(Stammlösung)} = Konzentration _{(Ziellösung)} × Volumen _{(Ziellösung)}

Konzentration _{(Stammlösung)} Konzentration _{(Stammlösung)}

Volumen _{(Stammlösung)} Volumen _{(Stammlösung)}

Konzentration _{(Ziellösung)} Konzentration _{(Ziellösung)}

Volumen _{(Ziellösung)} Volumen _{(Ziellösung)}

Reinheit & Dokumentation

Select Batch:

Reinheit: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (271 KB)
SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

Verweise

[1]. Kasper Harpsøe, et al. Prediction of the binding mode of biarylpropylsulfonamide allosteric AMPA receptor modulators based on docking, GRID molecular interaction fields and 3D-QSAR analysis. J Mol Graph Model. 2008 Jan;26(5):874-83. https://pubmed.ncbi.nlm.nih.gov/17644444/ [Content Brief]

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Complete Stock Solution Preparation Table

Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg
DMSO	1 mM	2.9812 mL	14.9058 mL	29.8116 mL	74.5290 mL
	5 mM	0.5962 mL	2.9812 mL	5.9623 mL	14.9058 mL
	10 mM	0.2981 mL	1.4906 mL	2.9812 mL	7.4529 mL
	15 mM	0.1987 mL	0.9937 mL	1.9874 mL	4.9686 mL
	20 mM	0.1491 mL	0.7453 mL	1.4906 mL	3.7264 mL
	25 mM	0.1192 mL	0.5962 mL	1.1925 mL	2.9812 mL
	30 mM	0.0994 mL	0.4969 mL	0.9937 mL	2.4843 mL
	40 mM	0.0745 mL	0.3726 mL	0.7453 mL	1.8632 mL
	50 mM	0.0596 mL	0.2981 mL	0.5962 mL	1.4906 mL
	60 mM	0.0497 mL	0.2484 mL	0.4969 mL	1.2421 mL
	80 mM	0.0373 mL	0.1863 mL	0.3726 mL	0.9316 mL
	100 mM	0.0298 mL	0.1491 mL	0.2981 mL	0.7453 mL

Keywords

MOQ

Minimum order quantity

100 mg

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Biologische Aktivität
- Beschreibung
- In Vitro
Chemical Information
Lösungsmittel & Löslichkeit
- In Vitro
Reinheit & Dokumentation
Verweise

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AMPA receptor modulator-3

Bioactive Compound Library Max

Bioactive Compound Library

Membrane Transporter/Ion Channel Compound Library

Neuronal Signaling Compound Library

Neurotransmitter Receptor Compound Library

Membrane Protein-targeted Compound Library

Membrane Receptor-targeted Compound Library

Ion Channel Compound Library

Allosteric Modulators (AMs) Compound Library

MCE Bioactive Compound Library

High-Throughput Bioactive Compound Library

Alle iGluR Isoform-spezifische Produkte anzeigen

Biologische Aktivität

Chemical Information

Lösungsmittel & Löslichkeit

Reinheit & Dokumentation

Verweise

Help & FAQs

Complete Stock Solution Preparation Table

AMPA receptor modulator-3

Bioactive Compound Library Max

Bioactive Compound Library

Membrane Transporter/Ion Channel Compound Library

Neuronal Signaling Compound Library

Neurotransmitter Receptor Compound Library

Membrane Protein-targeted Compound Library

Membrane Receptor-targeted Compound Library

Ion Channel Compound Library

Allosteric Modulators (AMs) Compound Library

MCE Bioactive Compound Library

High-Throughput Bioactive Compound Library

Alle iGluR Isoform-spezifische Produkte anzeigen

Biologische Aktivität

Chemical Information

Lösungsmittel & Löslichkeit

Reinheit & Dokumentation

Verweise

Help & FAQs

Complete Stock Solution Preparation Table

AMPA receptor modulator-3 Related Classifications

HY-122150 Related Classifications