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Art. -Nr.: HY-N17948

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Isolobetyol

Isolobetyol is a polyacetylene found in whole plants of Lobelia chinensis. Isolobetyol shows cytotoxic effects against cancer cells. Isolobetyol can be used for the research of cancer, such as human lung cancer and biphasic mesothelioma.

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CAS. Nr.: 1621230-88-3
Formel: C₁₄H₁₈O₃
Molecular Weight:234.29

Speicherung:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (263 KB)

Isolobetyol Chemical Structure

CAS. Nr.: 1621230-88-3

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Biologische Aktivität
- Beschreibung
- In Vitro
Chemical Information
Reinheit & Dokumentation
Verweise
Calculators
Help & FAQs
Classifications
Bioz

Biologische Aktivität

Beschreibung

In Vitro

Isolobetyol (Compound 8) (48 h) exhibits moderate cytotoxic activity against MSTO-211H biphasic mesothelioma cells and NCI-H292 human lung mucoepidermoid carcinoma cells, with IC₅₀ values of 12.36 μM and 9.31 μM, respectively^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Cell Cytotoxicity Assay^[1]

Cell Line:

NCI-H292 human lung mucoepidermoid carcinoma cells, MSTO-211H biphasic mesothelioma cells
Concentration:

IC₅₀ 9.31 μM (NCI-H292); IC₅₀ 12.36 μM (MSTO-211H)
Incubation Time:

48 h
Result:

Exhibited moderate cytotoxic activity with an IC₅₀ of 12.36 μM against MSTO-211H cells.
Showed moderate cytotoxic activity with an IC₅₀ of 9.31 μM against NCI-H292 cells.

Chemical Information

CAS. Nr. 1621230-88-3
Molecular Weight 234.29
Formel C₁₄H₁₈O₃
SMILES

OCCC/C=C/C(O)C(O)C#CC#C/C=C\C
Structure Classification
- Others
Initial Source
Versand

Room temperature in continental US; may vary elsewhere.
Speicherung

Please store the product under the recommended conditions in the Certificate of Analysis.

Reinheit & Dokumentation

Select Batch:

Reinheit: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (263 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

Verweise

[1]. Yang S, et al. Chemical constituents of Lobelia chinensis. Fitoterapia. 2014;93:168-174. [Content Brief]

Calculators

Molaritätsrechner

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Konzentration Konzentration

Volumen Volumen

Molecular Weight Molecular Weight

Verdünnungsrechner

Konzentration _{(Stammlösung)} × Volumen _{(Stammlösung)} = Konzentration _{(Ziellösung)} × Volumen _{(Ziellösung)}

Konzentration _{(Stammlösung)} Konzentration _{(Stammlösung)}

Volumen _{(Stammlösung)} Volumen _{(Stammlösung)}

Konzentration _{(Ziellösung)} Konzentration _{(Ziellösung)}

Volumen _{(Ziellösung)} Volumen _{(Ziellösung)}

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Bioz

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MOQ

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100 mg

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