In vivo therapeutic effect of gatifloxacin on BALB/c mice infected with Nocardia brasiliensis

  • Antimicrob Agents Chemother. 2008 Apr;52(4):1549-50. doi: 10.1128/AAC.00148-08.
Alejandra Daw-Garza  1 ,  Oliverio Welsh ,  Salvador Said-Fernández ,  Hector Gerardo Lozano-Garza ,  Noemi Waksman de Torres ,  Norma Cavazos Rocha ,  Jorge Ocampo-Candiani ,  Lucio Vera-Cabrera
Affiliations
  • 1. Servicio de Dermatología, Hospital Universitario José E González, Monterrey, NL, México.
PMID: 18285484 DOI: 10.1128/AAC.00148-08
Abstract

In the present work, we evaluated the effect of gatifloxacin on the evolution of experimental murine Infection with Nocardia brasiliensis using linezolid as a control. Gatifloxacin was injected subcutaneously at 100 mg/kg body weight every 8 h for 4 weeks. This compound was equally as efficient as linezolid in reducing the production of lesions.

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