Fresolimumab

Human IgG4 kappa

Immobilized TGF beta 1/TGFB1 Protein, Human can bind Fresolimumab. The EC₅₀ for this effect is 67.28 ng/mL.

Flow Cytometry analysis of PC-3 cells labelling TGFB1 (red) with Fresolimumab (anti-TGFB1) (HY-P99020). Goat Anti-Human IgG (Alexa Fluor 488) (HY-P83776) at a dilution of 1/1000 was used as the secondary antibody. Blue-Human IgG4 kappa (HY-P99003). Black-Unlabelled control, cells without incubation with primary antibody.

Fresolimumab purchased from MedChemExpress. Usage Cited in: Cells. 2023 Jun 14;12(12):1624. [Abstract]

Customer Validation
Fresolimumab (Neutralizing antibody against TGF-βs) (10 μg/mL; 7 days). Illustration of cell morphology by phase-contrast images. The images were acquired using a phase-contrast microscope with X10 objective. Cropped images were used to illustrate cell morphology. Scale bar = 100 µm.

Fresolimumab purchased from MedChemExpress. Usage Cited in: Cells. 2023 Jun 14;12(12):1624. [Abstract]

Customer Validation
Fresolimumab (Neutralizing antibody against TGF-βs) (10 μg/mL; 4 weeks). Illustrative images. Cell lateral membranes were stained in green by NCAM and the nuclei were counter-stained in blue using DAPI. A higher magnification (X40) was added in order to show the cell morphology. The images were taken in the center of each well. Images of the same magnification were acquired with the same parameters. The scale bar was 200 µm for X10 images and 50 µm for X40 images.