1. Membrane Transporter/Ion Channel Neuronal Signaling
  2. Calcium Channel
  3. Barnidipine

Barnidipine  (Synonyms: Mepirodipine; YM-09730-5 Free base)

Cat. No.: HY-107322A
Handling Instructions

Barnidipine (Mepirodipine) is an L-type calcium antagonist (CaA) with high affinity for [3H] initrendipine binding sites (Ki=0.21 nmol/l), has selective action against CaA receptors. Barnidipine (Mepirodipine) is an antihypertensive agent and acts by the reduction of peripheral vascular resistance secondary to its vasodilatory action.

For research use only. We do not sell to patients.

Barnidipine Chemical Structure

Barnidipine Chemical Structure

CAS No. : 104713-75-9

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Description

Barnidipine (Mepirodipine) is an L-type calcium antagonist (CaA) with high affinity for [3H] initrendipine binding sites (Ki=0.21 nmol/l), has selective action against CaA receptors[1]. Barnidipine (Mepirodipine) is an antihypertensive agent and acts by the reduction of peripheral vascular resistance secondary to its vasodilatory action[2].

IC50 & Target

L-type calcium channel

 

Molecular Weight

491.54

Formula

C27H29N3O6

CAS No.
SMILES

O=C(C1=C(C)NC(C)=C(C(O[C@@H]2CN(CC3=CC=CC=C3)CC2)=O)[C@H]1C4=CC=CC([N+]([O-])=O)=C4)OC

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Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Barnidipine
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HY-107322A
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