GTP-binding nuclear protein Ran

[1]. K Ribbeck, et al. NTF2 mediates nuclear import of Ran. EMBO J. 1998 Nov 16;17(22):6587-98. [Content Brief]

[2]. Fang Xia, et al. A survivin-ran complex regulates spindle formation in tumor cells. Mol Cell Biol. 2008 Sep;28(17):5299-311. [Content Brief]

[3]. M Ren, et al. Ran/TC4: a small nuclear GTP-binding protein that regulates DNA synthesis. J Cell Biol. 1993 Jan;120(2):313-23. [Content Brief]

[4]. D Görlich, et al. Identification of different roles for RanGDP and RanGTP in nuclear protein import. EMBO J. 1996 Oct 15;15(20):5584-94. [Content Brief]

[5]. Xiaoling Bao, et al. Mitosis-specific acetylation tunes Ran effector binding for chromosome segregation. J Mol Cell Biol. 2018 Feb 1;10(1):18-32. [Content Brief]

[6]. Masako Koyama, et al. An allosteric mechanism to displace nuclear export cargo from CRM1 and RanGTP by RanBP1. EMBO J. 2010 Jun 16;29(12):2002-13. [Content Brief]

[7]. I Palacios, et al. RAN/TC4 mutants identify a common requirement for snRNP and protein import into the nucleus. J Cell Biol. 1996 May;133(3):485-94. [Content Brief]

[8]. C Klebe, et al. Interaction of the nuclear GTP-binding protein Ran with its regulatory proteins RCC1 and RanGAP1. Biochemistry. 1995 Jan 17;34(2):639-47. [Content Brief]

[9]. William Moore, et al. Targeting of RCC1 to chromosomes is required for proper mitotic spindle assembly in human cells. Curr Biol. 2002 Aug 20;12(16):1442-7. [Content Brief]

[10]. F R Bischoff, et al. RanBP1 is crucial for the release of RanGTP from importin beta-related nuclear transport factors. FEBS Lett. 1997 Dec 15;419(2-3):249-54. [Content Brief]

[11]. L Renault, et al. Structural basis for guanine nucleotide exchange on Ran by the regulator of chromosome condensation (RCC1). Cell. 2001 Apr 20;105(2):245-55. [Content Brief]

[12]. R E Carazo-Salas, et al. Generation of GTP-bound Ran by RCC1 is required for chromatin-induced mitotic spindle formation. Nature. 1999 Jul 8;400(6740):178-81. [Content Brief]

[13]. Metin Aksu, et al. Structure of the exportin Xpo4 in complex with RanGTP and the hypusine-containing translation factor eIF5A. Nat Commun. 2016 Jun 16;7:11952. [Content Brief]

[14]. E Izaurralde, et al. The asymmetric distribution of the constituents of the Ran system is essential for transport into and out of the nucleus. EMBO J. 1997 Nov 3;16(21):6535-47. [Content Brief]

[15]. P W Hsiao, et al. The linkage of Kennedy's neuron disease to ARA24, the first identified androgen receptor polyglutamine region-associated coactivator. J Biol Chem. 1999 Jul 16;274(29):20229-34. [Content Brief]

[16]. Marta Sanz-García, et al. Proteomics identification of nuclear Ran GTPase as an inhibitor of human VRK1 and VRK2 (vaccinia-related kinase) activities. Mol Cell Proteomics. 2008 Nov;7(11):2199-214. [Content Brief]

[17]. Till Rudack, et al. Catalysis of GTP hydrolysis by small GTPases at atomic detail by integration of X-ray crystallography, experimental, and theoretical IR spectroscopy. J Biol Chem. 2015 Oct 2;290(40):24079-90. [Content Brief]

[18]. F Melchior, et al. Inhibition of nuclear protein import by nonhydrolyzable analogues of GTP and identification of the small GTPase Ran/TC4 as an essential transport factor. J Cell Biol. 1993 Dec;123(6 Pt 2):1649-59. [Content Brief]

[19]. J Moroianu, et al. Nuclear protein import: Ran-GTP dissociates the karyopherin alphabeta heterodimer by displacing alpha from an overlapping binding site on beta. Proc Natl Acad Sci U S A. 1996 Jul 9;93(14):7059-62. [Content Brief]

[20]. Daisuke Yamashita, et al. Human DNA replication-related element binding factor (hDREF) self-association via hATC domain is necessary for its nuclear accumulation and DNA binding. J Biol Chem. 2007 Mar 9;282(10):7563-75. [Content Brief]