CBR-096-4
CBR-096-4 is a derivative of Itraconazole (HY-17514). CBR-096-4 is an orally active antifibrotic agent with no CYP3A4 inhibitory activity. CBR-096-4 inhibits the formation of matrix-secreting activated myofibroblasts (MFBs) from multiple tissue types. CBR-096-4 inhibits Hedgehog reporter activity (GLI-LUC), VEGF-dependent growth, and αSMA-LUC reporter activity. CBR-096-4 can be used for research of fibrosis.
For research use only. We do not sell to patients.
- CAS No.: 1776931-05-5
- Formula: C35H40N8O4
- Molecular Weight:636.74
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
Chemical Information
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CAS No. 1776931-05-5
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Molecular Weight 636.74
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Formula C35H40N8O4
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SMILES
O=C1N(C(C)CC)N=CN1C2=CC=C(N3CCN(C4=CC=C(OC[C@@H]5O[C@](C6=CC=CC=C6)(CN7N=CC=N7)OC5)C=C4)CC3)C=C2
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)