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Cat. No.: HY-B2237A

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Lysozyme chloride

11 Cited Publications

Customer Review

Based on 11 publication(s) in Google Scholar

Lysozyme chloride is a bactericidal enzyme, and it lyses gram-positive bacteria. Lysozyme chloride can also be used for the research of HIV infection and pulmonary emphysema.

For research use only. We do not sell to patients.

CAS No.: 9066-59-5

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Lysozyme chloride Chemical Structure

CAS No.: 9066-59-5

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- In Vitro
- In Vivo
Chemical Information
Publications (11)
Solvent & Solubility
- In Vitro
Purity & Documentation
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

Description

Lysozyme chloride is a bactericidal enzyme, and it lyses gram-positive bacteria. Lysozyme chloride can also be used for the research of HIV infection and pulmonary emphysema^[1]^[2]^[3].

All HIV Isoforms :

In Vitro

Lysozyme is an ubiquitous enzyme. The hen egg is the most abundant source of Lysozyme, which constitutes approximately 3.4% of the albumen proteins. Lysozyme is a natural antimicrobial that hydrolyzes the β(1-4) glycosidic linkage between N-acetylmuramic acid and N-acetylglucosamine found in the peptidoglycan layer of the bacterial cell wall and causing cell lysis. The bactericidal effect of Lysozyme chloride is primarily limited to gram-positive bacteria, including pathogens such as Listeria monocytogenes and certain Clostridium species as well as some spoilage organisms, including thermophilic spore-forming bacteria and certain yeasts. The gram-negative bacteria are more resistant to Lysozyme chloride action because of their complex cell wall structure^[1].
Lysozyme (1 mg/mL) chloride impairs the ability of hyaluronan (HA) to prevent elastase injury to elastic fibers^[3].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

In Vivo

Syrian hamsters exposes to aerosolized Lysozyme (20 mg in 20 ml of water; 50 min) chloride prior to elastase administration showes significantly increased airspace enlargement^[3].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS No. 9066-59-5
Appearance Solid
Color White to off-white
SMILES

[Lysozyme chloride]
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Publications (11)

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Journal Impact Factor

Cancer Cell

Alistipes finegoldii augments the efficacy of immunotherapy against solid tumors. [Abstract]

2025 Jul 17:S1535-6108(25)00273-9. PMID: 40712567
Pharmaceutics

Development and Optimization of Ionic Strength-Responsive Lipid-Polymer Hybrid Nanoparticles for Buccal Protein Delivery. [Abstract]

2026 Jun 11;18(6):719. PMID: 42357335
Pharmaceutics

2026 Feb;18(2):275.
Pharmaceutics

Quality by Design-Based Development of Solid Self-Emulsifying Drug Delivery System (SEDDS) as a Potential Carrier for Oral Delivery of Lysozyme. [Abstract]

2023 Mar 20;15(3):995. PMID: 36986855
Appl Surf Sci

2020, 145332.
J Drug Deliv Sci Technol

21 July 2021, 102714.
iScience

Radiotolerance of N-cycle bacteria and their transcriptomic response to low-dose space-analogue ionizing irradiation. [Abstract]

2024 Mar 27;27(5):109596. PMID: 38638570
iScience

Optimization of RNA extraction for bacterial whole transcriptome studies of low-biomass samples. [Abstract]

2022 Oct 9;25(11):105311. PMID: 36345334

Lysozyme chloride purchased from MedChemExpress. Usage Cited in: iScience. 2022 Oct 9;25(11):105311. [Abstract]

Amount of RNA in ng per 10⁶ cells from 5 mL N. europaea cultures extracted with NucleoSpin RNA XS kit preceded by enzymatic digestion with lysozyme (1-3 mg/mL) solution. The effect on RNA yield and quality of different lysozyme concentrations, different volumes of RA1 buffer after lysozyme digestion and different lysozyme incubation times are shown.

Lysozyme chloride purchased from MedChemExpress. Usage Cited in: iScience. 2022 Oct 9;25(11):105311. [Abstract]

Examples of electropherograms generated from RNA samples with the Agilent BioAnalyzer 2100 represents an RNA sample extracted with the NS XS kit after pretreatment with a 1 mg/mL lysozyme solution and 15 min of incubation at 37°C with a RIN of 10.0.

Lysozyme chloride purchased from MedChemExpress. Usage Cited in: iScience. 2022 Oct 9;25(11):105311. [Abstract]

The protocol on N. winogradskyi cultures using higher lysozyme concentrations, with different incubation times with 1 mg/mL lysozyme solution.

Lysozyme chloride purchased from MedChemExpress. Usage Cited in: iScience. 2022 Oct 9;25(11):105311. [Abstract]

The protocol on N. winogradskyi cultures using higher lysozyme concentrations, with the addition of Proteinase K (ProtK) to a 15 mg/mL lysozyme solution and/or vortexing (indicated by V).

Lysozyme chloride purchased from MedChemExpress. Usage Cited in: iScience. 2022 Oct 9;25(11):105311. [Abstract]

The protocol on N. winogradskyi cultures using various lysozyme concentrations during shaking incubation at 1,400 rpm for 15 min.
STAR Protoc

RNA extraction protocol from low-biomass bacterial Nitrosomonas europaea and Nitrobacter winogradskyi cultures for whole transcriptome studies. [Abstract]

2023 Jun 21;4(3):102358. PMID: 37347668
ArXiv

2025 Oct 3.
Universite Grenoble Alpes

2025 Sep 30.

Solvent & Solubility

In Vitro:

H₂O : ≥ 4 mg/mL

* "≥" means soluble, but saturation unknown.

View the Complete Stock Solution Preparation Table

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (270 KB)
SDS (418 KB)
- English - EN (418 KB)
- Français - FR (418 KB)
- Deutsch - DE (418 KB)
- Norwegian - NO (418 KB)
- Español - ES (418 KB)
- Swedish - SV (418 KB)
- Italian - IT (418 KB)
- Korean - KR (418 KB)
- Portuguese - PT (418 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Banerjee P, et al. Influence of carbon dioxide on the activity of chicken egg white lysozyme. Poult Sci. 2011 Apr;90(4):889-95. [Content Brief]

[2]. Jing T, et al. Magnetic molecularly imprinted nanoparticles for recognition of lysozyme. Biosens Bioelectron. 2010 Oct 15;26(2):301-6. [Content Brief]

[3]. Cantor JO, et al. The effect of lysozyme on elastase-mediated injury. Exp Biol Med (Maywood). 2002 Feb;227(2):108-13. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Keywords

Lysozyme chloride

11 Cited Publications

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Biological Activity
- Description
- In Vitro
- In Vivo
Chemical Information
Publications (11)
Solvent & Solubility
- In Vitro
Purity & Documentation
References

1/16
1/16

Lysozyme chloride purchased from MedChemExpress. Usage Cited in: iScience. 2022 Oct 9;25(11):105311. [Abstract]

Customer Validation
Amount of RNA in ng per 10⁶ cells from 5 mL N. europaea cultures extracted with NucleoSpin RNA XS kit preceded by enzymatic digestion with lysozyme (1-3 mg/mL) solution. The effect on RNA yield and quality of different lysozyme concentrations, different volumes of RA1 buffer after lysozyme digestion and different lysozyme incubation times are shown.
1/16

Lysozyme chloride purchased from MedChemExpress. Usage Cited in: iScience. 2022 Oct 9;25(11):105311. [Abstract]

Customer Validation
Examples of electropherograms generated from RNA samples with the Agilent BioAnalyzer 2100 represents an RNA sample extracted with the NS XS kit after pretreatment with a 1 mg/mL lysozyme solution and 15 min of incubation at 37°C with a RIN of 10.0.
1/16

Lysozyme chloride purchased from MedChemExpress. Usage Cited in: iScience. 2022 Oct 9;25(11):105311. [Abstract]

Customer Validation
The protocol on N. winogradskyi cultures using higher lysozyme concentrations, with different incubation times with 1 mg/mL lysozyme solution.
1/16

Lysozyme chloride purchased from MedChemExpress. Usage Cited in: iScience. 2022 Oct 9;25(11):105311. [Abstract]

Customer Validation
The protocol on N. winogradskyi cultures using higher lysozyme concentrations, with the addition of Proteinase K (ProtK) to a 15 mg/mL lysozyme solution and/or vortexing (indicated by V).
1/16

Lysozyme chloride purchased from MedChemExpress. Usage Cited in: iScience. 2022 Oct 9;25(11):105311. [Abstract]

Customer Validation
The protocol on N. winogradskyi cultures using various lysozyme concentrations during shaking incubation at 1,400 rpm for 15 min.

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Lysozyme chloride

Publications Citing Use of MedChemExpress (MCE) Lysozyme chloride

All HIV Isoforms

Biological Activity

Chemical Information

Publications (11)

Solvent & Solubility

Purity & Documentation

References

Calculators

Help & FAQs

Lysozyme chloride Related Classifications

HY-B2237A Related Classifications