RKI-1313
Based on 1 Customer Validation
RKI-1313 is a ROCK inhibitor with IC50s of 34, 8 µM for ROCK 1 and ROCK 2, respectively. RKI-1313 shows little effect on the phosphorylation levels of ROCK substrates, migration, invasion or anchorage-independent growth.
For research use only. We do not sell to patients.
- Purity: 98.2%
- CAS No.: 1342276-76-9
- Formula: C17H16N4O2S
- Molecular Weight:340.40
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Storage:Powder -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
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ROCK1 34 μM (IC50) |
ROCK2 8 μM (IC50) |
Chemical Information
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CAS No. 1342276-76-9
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Appearance Solid
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Molecular Weight 340.40
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Formula C17H16N4O2S
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Color White to off-white
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SMILES
COC1=CC=CC(CNC(NC2=NC(C3=CC=NC=C3)=CS2)=O)=C1
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
DMSO : 30 mg/mL (88.13 mM; Need ultrasonic and warming; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (268 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 2.9377 mL | 14.6886 mL | 29.3772 mL | 73.4430 mL |
| 5 mM | 0.5875 mL | 2.9377 mL | 5.8754 mL | 14.6886 mL | |
| 10 mM | 0.2938 mL | 1.4689 mL | 2.9377 mL | 7.3443 mL | |
| 15 mM | 0.1958 mL | 0.9792 mL | 1.9585 mL | 4.8962 mL | |
| 20 mM | 0.1469 mL | 0.7344 mL | 1.4689 mL | 3.6722 mL | |
| 25 mM | 0.1175 mL | 0.5875 mL | 1.1751 mL | 2.9377 mL | |
| 30 mM | 0.0979 mL | 0.4896 mL | 0.9792 mL | 2.4481 mL | |
| 40 mM | 0.0734 mL | 0.3672 mL | 0.7344 mL | 1.8361 mL | |
| 50 mM | 0.0588 mL | 0.2938 mL | 0.5875 mL | 1.4689 mL | |
| 60 mM | 0.0490 mL | 0.2448 mL | 0.4896 mL | 1.2241 mL | |
| 80 mM | 0.0367 mL | 0.1836 mL | 0.3672 mL | 0.9180 mL |
RKI-1313 Related Classifications
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