Tryptamine hydrochloride
Based on 2 publication(s) in Google Scholar
Tryptamine hydrochloride belongs to the class of indole alkaloids and is a derivative of the amino acid tryptophan. Tryptamine hydrochloride is psychoactive and acts as a neurotransmitter in the body, affecting mood, perception and cognition. In its hydrochloride form, Tryptamine hydrochloride hydrochloride, it is commonly used as a research chemical and as a starting material for the synthesis of other organic compounds. It can also occur naturally in certain plants and animals, including fungi and mammals. Due to the psychoactive properties of Tryptamine hydrochloride and its derivatives, its use and possession are controlled substances in many countries.
For research use only. We do not sell to patients.
- Purity: 99.98%
- CAS No.: 343-94-2
- Formula: C10H13ClN2
- Molecular Weight:196.68
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Storage:
4°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
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Help & FAQs
Publications Citing Use of MedChemExpress (MCE) Tryptamine hydrochloride
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Customer Validation & Images
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In Vivo Efficacy Study
Biological Activity
Tryptamine (hydrochloride) is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 343-94-2
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Appearance Solid
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Molecular Weight 196.68
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Formula C10H13ClN2
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Color White to off-white
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SMILES
NCCC1=CNC2=CC=CC=C12.Cl
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
4°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Publications (2)
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Journal Impact Factor
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Most Recent
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Nat Neurosci
2026 Jun 19. PMID: 42321470 -
Pest Manag Sci
The native rice leaf folder can enhance rice resistance against the invasive fall armyworm by inducing the jasmonate-mediated tryptophan metabolism pathway. [Abstract]2026 May;82(5):5026-5039. PMID: 41635108
Tryptamine hydrochloride purchased from MedChemExpress. Usage Cited in: Pest Manag Sci. 2026 May;82(5):5026-5039. [Abstract]
Mean body weight (±SE; n = 7 biological replicates) and representative photographs of FAW neonates after feeding for 4 days on artificial diets supplemented with Tryptamine at 0, 1, 10 or 100 μg/g. Tryptamine significantly inhibited FAW growth, resulting in reduced larval weight in a dose-dependent manner.
Solvent & Solubility
DMSO : 100 mg/mL (508.44 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Select the appropriate dissolution method based on your experimental animal and administration route.
- For the following dissolution methods, please ensure to first prepare a clear stock solution using an In Vitro approach and then sequentially add co-solvents:
- To ensure reliable experimental results, the clarified stock solution can be appropriately stored based on storage conditions. As for the working solution for In Vivo experiments, it is recommended to prepare freshly and use it on the same day.
- The percentages shown for the solvents indicate their volumetric ratio in the final prepared solution. If precipitation or phase separation occurs during preparation, heat and/or sonication can be used to aid dissolution.
Add each solvent one by one: 10% DMSO 40% PEG300 5% Tween-80 45% Saline
Solubility: ≥ 2.5 mg/mL (12.71 mM); Clear solution
This protocol yields a clear solution of ≥ 2.5 mg/mL (saturation unknown).
Taking 1 mL working solution as an example, add 100 μL DMSO stock solution (25.0 mg/mL) to 400 μL PEG300, and mix evenly; then add 50 μL Tween-80 and mix evenly; then add 450 μL Saline to adjust the volume to 1 mL.
Preparation of Saline: Dissolve 0.9 g sodium chloride in ddH₂O and dilute to 100 mL to obtain a clear Saline solution.
Add each solvent one by one: 10% DMSO 90% (20% SBE-β-CD in Saline)
Solubility: ≥ 2.5 mg/mL (12.71 mM); Clear solution
This protocol yields a clear solution of ≥ 2.5 mg/mL (saturation unknown).
Taking 1 mL working solution as an example, add 100 μL DMSO stock solution (25.0 mg/mL) to 900 μL 20% SBE-β-CD in Saline, and mix evenly.
Preparation of 20% SBE-β-CD in Saline (4°C, storage for one week): 2 g SBE-β-CD powder is dissolved in 10 mL Saline, completely dissolve until clear.
Please enter the basic information of animal experiments:
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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Please enter your animal formula composition:
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%DMSO +
Recommended: Keep the proportion of DMSO in working solution below 2% if your animal is weak.
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%+
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+%Tween-80 + +
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%Saline +
The co-solvents required include: DMSO, . All of co-solvents are available by MedChemExpress (MCE). , Tween 80. All of co-solvents are available by MedChemExpress (MCE).
Working solution concentration: 0.22 mg/mL
Method for preparing stock solution: mg drug dissolved in μL DMSO. Stock solution concentration: mg/mL. * In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
1. Take μL DMSO stock solution;
2. Add μL .
μL , mix evenly;
3. Then add μL Tween 80, mix evenly;
4. Then add μL
Please ensure that the stock solution in the first step is dissolved to a clear state, and add co-solvents in sequence. You can use ultrasonic heating (ultrasonic cleaner, recommended frequency 20-40 kHz), vortexing, etc. to assist dissolution.
Purity & Documentation
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Data Sheet (250 KB)
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SDS (614 KB)
- English - EN (614 KB)
- Français - FR (614 KB)
- Deutsch - DE (614 KB)
- Norwegian - NO (614 KB)
- Español - ES (614 KB)
- Swedish - SV (614 KB)
- Italian - IT (614 KB)
- Korean - KR (614 KB)
- Portuguese - PT (614 KB)
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Handling Instructions (2659 KB)
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 5.0844 mL | 25.4220 mL | 50.8440 mL | 127.1100 mL |
| 5 mM | 1.0169 mL | 5.0844 mL | 10.1688 mL | 25.4220 mL | |
| 10 mM | 0.5084 mL | 2.5422 mL | 5.0844 mL | 12.7110 mL | |
| 15 mM | 0.3390 mL | 1.6948 mL | 3.3896 mL | 8.4740 mL | |
| 20 mM | 0.2542 mL | 1.2711 mL | 2.5422 mL | 6.3555 mL | |
| 25 mM | 0.2034 mL | 1.0169 mL | 2.0338 mL | 5.0844 mL | |
| 30 mM | 0.1695 mL | 0.8474 mL | 1.6948 mL | 4.2370 mL | |
| 40 mM | 0.1271 mL | 0.6356 mL | 1.2711 mL | 3.1778 mL | |
| 50 mM | 0.1017 mL | 0.5084 mL | 1.0169 mL | 2.5422 mL | |
| 60 mM | 0.0847 mL | 0.4237 mL | 0.8474 mL | 2.1185 mL | |
| 80 mM | 0.0636 mL | 0.3178 mL | 0.6356 mL | 1.5889 mL | |
| 100 mM | 0.0508 mL | 0.2542 mL | 0.5084 mL | 1.2711 mL |
Tryptamine hydrochloride Related Classifications
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