Ac-RYYRWK-NH2
Ac-RYYRWK-NH2 is a potent and selective partial agonist for the nociceptin receptor (NOP), [3H]Ac-RYYRWK-NH2 binds to rat cortical membranes ORL1 with a Kd of 0.071 nM, but has no affinity for µ-, κ- or δ-opioid receptors.
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- CAS No.: 200959-47-3
- Formule: C49H69N15O9
- Masse moléculaire:1012.17
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Activité biologique
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Chemical Information
- Pureté et documentation
- Références
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Help & FAQs
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Activité biologique
Kd: 0.071 nM (ORL1 in rat cortical membranes)[1]
Chemical Information
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CAS No. 200959-47-3
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Masse moléculaire 1012.17
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Formule C49H69N15O9
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Sequence Shortening
Ac-RYYRWK-NH2
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
[1]. C T Dooley, et al. Binding and in vitro activities of peptides with high affinity for the nociceptin/orphanin FQ receptor, ORL1.J Pharmacol Exp Ther. 1997 Nov;283(2):735-41. [Content Brief]
[2]. M Ho, et al, Characterization of the ORL(1) receptor on adrenergic nerves in the rat anococcygeus muscle. Br J Pharmacol. 2000 Sep;131(2):349-55. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Ac-RYYRWK-NH2 Related Classifications
HY-P1316 Related Classifications
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