C3N-Dbn-Trp2
C3N-Dbn-Trp2 is an inhibitor for ATP-binding cassette transporter ABCB1. C3N-Dbn-Trp2 inhibits the ABCB1-mediated Rhodamine 123 (HY-D0816) efflux in cells HEK293T and HCT-15 with IC50 of 5.9 µM and 2.2 µM. C3N-Dbn-Trp2 inhibits the Doxorubicin (HY-15142A) efflux, enhances the cytotoxicity of Doxorubicin in ABCB1-expressing cells.
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- CAS No.: 2631659-57-7
- Formule: C36H32N4O2
- Masse moléculaire:552.66
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Activité biologique
Chemical Information
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CAS No. 2631659-57-7
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Masse moléculaire 552.66
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Formule C36H32N4O2
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SMILES
[H][C@@]12N(CC3=CC=CC=C3)C4=CC=CC=C4[C@]1(CC5=CC=CC=C5)C[C@]6([H])N2C([C@@](CC7=CNC8=C7C=CC=C8)([H])NC6=O)=O
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
C3N-Dbn-Trp2 Related Classifications
HY-162714 Related Classifications
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