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Cabiralizumab

(Synonyms: FPA 008; Anti-Human CSF1R Recombinant Antibody)
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Cabiralizumab (FPA 008) is an anti-CSF1R monoclonal antibody (MAb). Cabiralizumab enhances T cell infiltration and antitumor T cell immune responses. Cabiralizumab inhibits the activation of osteoclasts and blocks bone destruction, and can be used in the research of rheumatoid arthritis (RA). Cabiralizumab can combine with Nivolumab (HY-P9903) for lung cancer research.

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  • Pureté: 99.73%
  • CAS No.: 1613144-80-1
  • Masse moléculaire:146.02 kDa
  • Stockage:

    Please store the product under the recommended conditions in the Certificate of Analysis.

  • Experimental Validation Results for Cabiralizumab
  • Experimental Validation Results for Cabiralizumab
  • Experimental Validation Results for Cabiralizumab
  • Cabiralizumab Chemical Structure
    Cabiralizumab Chemical Structure
CAS No.: 1613144-80-1
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Cabiralizumab Product Recommendations:

To place orders, for customer services and technical support, please contact:

609-228-6898
[email protected] [email protected]
Trouvez votre distributeur local Your local distributor: Hycultec GmbHHycultec
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Assay Types
  • 1/16

    Human IgG4 kappa

  • 1/16

    Immobilized Human M-CSFR/CSF1R Protein can bind Cabiralizumab. The EC50 for this effect is 2.465 ng/mL.

  • 1/16

    Flow cytometric analysis of 1.5X106 THP-1 cells labeling Cabiralizumab (HY-P99259, red). Cells were fixed with 4% paraformaldehyde. Then stained with the primary antibody at 1/200 dilution for an hour at 4℃. Goat Anti-Human IgG H&L (AF488) (HY-P83776) was used as the secondary antibody at 1/1,000 dilution for 30 minutes at 4℃. Human IgG4 kappa (HY-P99003, blue) was used as the isotype control.

  • Cabiralizumab Chemical Structure
    1/16
  • Cabiralizumab
  • Immobilized Human M-CSFR/CSF1R Protein can bind Cabiralizumab. The EC50 for this effect is 2.465 ng/mL.
  • Flow cytometric analysis of 1.5X106 THP-1 cells labeling Cabiralizumab (HY-P99259, red). Cells were fixed with 4% paraformaldehyde. Then stained with the primary antibody at 1/200 dilution for an hour at 4℃. Goat Anti-Human IgG H&L (AF488) (HY-P83776) was used as the secondary antibody at 1/1,000 dilution for 30 minutes at 4℃. Human IgG4 kappa (HY-P99003, blue) was used as the isotype control.