DL-Dithiothreitol-d10-1
DL-Dithiothreitol-d10-1 is the deuterated form of DL-dithiothreitol. DL-Dithiothreitol (DTT) is a strong reductant with anti-disulfidptosis activity. DL-Dithiothreitol is oxidized to form a stable six-membered ring with an internal disulfide bond.
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- CAS No.: 203633-21-0
- Formule: C4D10O2S2
- Masse moléculaire:164.31
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Activité biologique
Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Chemical Information
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CAS No. 203633-21-0
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Unlabeled Cas 3483-12-3
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Masse moléculaire 164.31
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Formule C4D10O2S2
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SMILES
[2H]SC([2H])([2H])[C@](O[2H])([2H])[C@@](O[2H])([2H])C([2H])([2H])S[2H]
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Synonyms
DTTl-d10-1
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216. [Content Brief]
[2]. Yao H, et al. Establishment of disulfidptosis-related LncRNA signature as biomarkers in colon adenocarcinoma[J]. Cancer Cell International, 2024, 24(1): 183. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)