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Cat. No.: HY-163334

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GGDPS-IN-1

GGDPS-IN-1 (Compound 37) is a geranylgeranyl diphosphate synthase (GGDPS) inhibitor with an IC₅₀ of 49.4 nM. GGDPS-IN-1 disrupts protein geranylgeranylation in myeloma cells.

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Formule: C₁₅H₂₈N₄O₆P₂
Masse moléculaire:422.35

Stockage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (265 KB)

GGDPS-IN-1 Chemical Structure

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Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Activité biologique
- Description
- IC₅₀ & Target
Chemical Information
Pureté et documentation
Références
Calculators
Help & FAQs
Classifications
Bioz

Activité biologique

Description

GGDPS-IN-1 (Compound 37) is a geranylgeranyl diphosphate synthase (GGDPS) inhibitor with an IC₅₀ of 49.4 nM. GGDPS-IN-1 disrupts protein geranylgeranylation in myeloma cells^[1].

IC₅₀ & Target

Geranylgeranyl Diphosphate Synthase (GGDPS)^[1]

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Chemical Information

Masse moléculaire 422.35
Formule C₁₅H₂₈N₄O₆P₂
SMILES

O=P(O)(C(CC1=CN(N=N1)CC/C=C(CC/C=C(C)/C)\C)(N)P(O)(O)=O)O
Livraison

Room temperature in continental US; may vary elsewhere.
Stockage

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureté et documentation

Select Batch:

Pureté: 99.98%

Assay: 99.98%

ee.: 99.98%

Fiche technique (265 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Instruction de manipulation (2659 KB)

Références

[1]. Gehrke NR, et al. α-Amino bisphosphonate triazoles serve as GGDPS inhibitors. Bioorg Med Chem Lett. 2024 Feb 17:129659. [Content Brief]

Calculators

Calculateur de molarité

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

Calculateur de dilution

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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MOQ

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100 mg

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Activité biologique
- Description
- IC₅₀ & Target
Chemical Information
Pureté et documentation
Références

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GGDPS-IN-1

Voir tous les produits spécifiques à Isoform Ras

Activité biologique

Chemical Information

Pureté et documentation

Références

Calculators

Help & FAQs

GGDPS-IN-1 Related Classifications

HY-163334 Related Classifications