CES2-IN-1
Based on 1 Customer Validation
CES2-IN-1 (Compound 24) is a reversible and selective CES2 inhibitor (IC50: 6.72 μM for human CES2). CES2-IN-1 reduces the level of CES2 in living cells. CES2-IN-1 is effective against Irinotecan (HY-16562)-induced delayed diarrhea and DSS-induced ulcerative colitis.
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- Pureté: 99.93%
- CAS No.: 2994634-52-3
- Formule: C16H11ClN4
- Masse moléculaire:294.74
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Stockage:
4°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Activité biologique
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Chemical Information
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Solvant et solubilité
- Pureté et documentation
- Références
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Help & FAQs
Activité biologique
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hCES2 6.72 μM (IC50) |
Chemical Information
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CAS No. 2994634-52-3
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Appearance Solid
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Masse moléculaire 294.74
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Formule C16H11ClN4
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Color Light yellow to yellow
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SMILES
ClC1=CC=CC2=C1N=C(C=C2)NC3=NC4=CC=CC=C4N3
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
4°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
Solvant et solubilité
DMSO : 10 mg/mL (33.93 mM; ultrasonic and warming and heat to 60°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Pureté et documentation
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Fiche technique (271 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Instruction de manipulation (2659 KB)
Références
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 3.3928 mL | 16.9641 mL | 33.9282 mL | 84.8205 mL |
| 5 mM | 0.6786 mL | 3.3928 mL | 6.7856 mL | 16.9641 mL | |
| 10 mM | 0.3393 mL | 1.6964 mL | 3.3928 mL | 8.4821 mL | |
| 15 mM | 0.2262 mL | 1.1309 mL | 2.2619 mL | 5.6547 mL | |
| 20 mM | 0.1696 mL | 0.8482 mL | 1.6964 mL | 4.2410 mL | |
| 25 mM | 0.1357 mL | 0.6786 mL | 1.3571 mL | 3.3928 mL | |
| 30 mM | 0.1131 mL | 0.5655 mL | 1.1309 mL | 2.8274 mL |
CES2-IN-1 Related Classifications
HY-155181 Related Classifications
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