IDO1/TDO-IN-7
IDO1/TDO-IN-7 (Compound 43b), an isoquinoline derivative, is a potent dual IDO1/TDO inhibitor, with IC50s of 0.31 μM and 0.08 μM, respectively. IDO1/TDO-IN-7 displays acceptable pharmacokinetic profiles and potent antitumor efficacy with low toxicity in B16-F10 tumor model.
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- Formule: C17H13F3N2O4S
- Masse moléculaire:398.36
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Activité biologique
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Chemical Information
- Pureté et documentation
- Références
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Help & FAQs
Activité biologique
IC50: 0.31 μM (IDO1) and 0.08 μM (TDO)[1]
Chemical Information
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Masse moléculaire 398.36
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Formule C17H13F3N2O4S
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SMILES
OC1=C2C(C=C(C3=CC=C(NS(=O)(C(F)(F)F)=O)C=C3)N=C2)=CC=C1OC
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
IDO1/TDO-IN-7 Related Classifications
HY-162962 Related Classifications
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