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Cat. No.: HY-162015

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LTA4H-IN-2

LTA4H-IN-2 (compound (S)-2 ) is an orally active inhibitor of Leukotriene A4 Hydrolase, with an IC₅₀ of <3 nM.

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CAS No.: 2851480-52-7
Formule: C₂₀H₁₉FN₆O₂
Masse moléculaire:394.40

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Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (267 KB)

LTA4H-IN-2 Chemical Structure

CAS No.: 2851480-52-7

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Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Activité biologique
- Description
- IC₅₀ & Target
Chemical Information
Pureté et documentation
Références
Calculators
Help & FAQs
Classifications
Bioz

Activité biologique

Description

LTA4H-IN-2 (compound (S)-2 ) is an orally active inhibitor of Leukotriene A4 Hydrolase, with an IC₅₀ of <3 nM^[1].

IC₅₀ & Target

IC50: <3 nM (Leukotriene A4 Hydrolase)^[1].

Voir tous les produits spécifiques à Isoform Aminopeptidase :

CD13
LTA4H

Chemical Information

CAS No. 2851480-52-7
Masse moléculaire 394.40
Formule C₂₀H₁₉FN₆O₂
SMILES

N[C@@H](CN1C=CC(C2=CC=C(OC3=NC=C(C4=CC=NN4)C=C3F)C=C2)=N1)CO
Livraison

Room temperature in continental US; may vary elsewhere.
Stockage

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureté et documentation

Select Batch:

Pureté: 99.98%

Assay: 99.98%

ee.: 99.98%

Fiche technique (267 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Instruction de manipulation (2659 KB)

Références

[1]. Gebhard Thoma, et al. Discovery of Amino Alcohols as Highly Potent, Selective, and Orally Efficacious Inhibitors of Leukotriene A4 Hydrolase. J Med Chem. 2023 Dec 14;66(23):16410-16425. [Content Brief]

Calculators

Calculateur de molarité

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

Calculateur de dilution

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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Activité biologique
- Description
- IC₅₀ & Target
Chemical Information
Pureté et documentation
Références

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LTA4H-IN-2

Voir tous les produits spécifiques à Isoform Aminopeptidase

Activité biologique

Chemical Information

Pureté et documentation

Références

Calculators

Help & FAQs

LTA4H-IN-2 Related Classifications

HY-162015 Related Classifications