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Cat. No.: HY-184026

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MAO-B-IN-58

MAO-B-IN-58 (Compound 2e) is a reversible, selective MAO-B inhibitor with an IC₅₀ of 170 nM against rat MAO-B. MAO-B-IN-58 is applicable for the research of Parkinson's disease and Alzheimer's disease.

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CAS No.: 898540-68-6
Formule: C₁₉H₁₄N₂O₂
Masse moléculaire:302.33

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Please store the product under the recommended conditions in the Certificate of Analysis.

MAO-B-IN-58 Chemical Structure

CAS No.: 898540-68-6

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Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Activité biologique
- Description
- IC₅₀ & Target
- In Vitro
Chemical Information
Pureté et documentation
Références
Calculators
Help & FAQs
Classifications
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Description

IC₅₀ & Target^[1]

MAO-B

170 nM (IC₅₀)

MAO-A

>1000 nM (IC₅₀)

Voir tous les produits spécifiques à Isoform Monoamine Oxidase :

MAO-A
MAO-B

In Vitro

MAO-B-IN-58 potently inhibits MAO-B in rat brain mitochondria with an IC₅₀ of 170 nM and does not inhibit MAO-A^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS No. 898540-68-6
Masse moléculaire 302.33
Formule C₁₉H₁₄N₂O₂
SMILES

CC1=CC2=C(C3=CC(OCC4=CC=CC=C4)=CC=C3C2=O)N=N1
Livraison

Room temperature in continental US; may vary elsewhere.
Stockage

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureté et documentation

Instruction de manipulation (2659 KB)

Références

[1]. Frédérick R, et al. Synthesis, structural reassignment, and biological activity of type B MAO inhibitors based on the 5H-indeno[1,2-c]pyridazin-5-one core. J Med Chem. 2006 Jun 15;49(12):3743-7. [Content Brief]

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How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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Activité biologique
- Description
- IC₅₀ & Target
- In Vitro
Chemical Information
Pureté et documentation
Références

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MAO-B-IN-58

Voir tous les produits spécifiques à Isoform Monoamine Oxidase

Activité biologique

Chemical Information

Pureté et documentation

Références

Calculators

Help & FAQs

MAO-B-IN-58 Related Classifications

HY-184026 Related Classifications