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Cat. No.: HY-136074

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Methyltetrazine-PEG4-aldehyde

Methyltetrazine-PEG4-aldehyde is a cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Methyltetrazine-PEG4-aldehyde is a click chemistry reagent, it contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups.

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CAS No.: 2446160-72-9
Formule: C₂₉H₃₆N₆O₇
Masse moléculaire:580.63

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Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (262 KB)

Methyltetrazine-PEG4-aldehyde Chemical Structure

CAS No.: 2446160-72-9

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- Description
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- In Vitro
Chemical Information
Pureté et documentation
Références
Calculators
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Description

Methyltetrazine-PEG4-aldehyde is a cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)^[1]. Methyltetrazine-PEG4-aldehyde is a click chemistry reagent, it contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups.

IC₅₀ & Target

Cleavable Linker

Voir tous les produits spécifiques à Isoform ADC Linkers :

In Vitro

ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS No. 2446160-72-9
Masse moléculaire 580.63
Formule C₂₉H₃₆N₆O₇
SMILES

CC1=NN=C(C2=CC=C(CNC(CCOCCOCCOCCOCCNC(C3=CC=C(C([H])=O)C=C3)=O)=O)C=C2)N=N1
Livraison

Room temperature in continental US; may vary elsewhere.
Stockage

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureté et documentation

Select Batch:

Pureté: 99.98%

Assay: 99.98%

ee.: 99.98%

Fiche technique (262 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Instruction de manipulation (2659 KB)

Références

[1]. Beck A, et al. Strategies and challenges for the next generation of antibody-drug conjugates. Nat Rev Drug Discov. 2017 May;16(5):315-337. [Content Brief]

Calculators

Calculateur de molarité

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Calculateur de dilution

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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Methyltetrazine-PEG4-aldehyde

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Chemical Information
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Références

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Methyltetrazine-PEG4-aldehyde

Voir tous les produits spécifiques à Isoform ADC Linkers

Activité biologique

Chemical Information

Pureté et documentation

Références

Calculators

Help & FAQs

Methyltetrazine-PEG4-aldehyde Related Classifications

HY-136074 Related Classifications