2446160-72-9
Chemical Structure
Methyltetrazine-PEG4-aldehyde
- CAS No.: 2446160-72-9
- Formula:C29H36N6O7
- Molecular Weight:580.63
IUPAC Name: 1-(4-formylbenzamido)-N-(4-(6-methyl-1,2,4,5-tetrazin-3-yl)benzyl)-3,6,9,12-tetraoxapentadecan-15-amide
InChIKey: AIEXSBMLTZDYSD-UHFFFAOYSA-N
SMILES: CC1=NN=C(C2=CC=C(CNC(CCOCCOCCOCCOCCNC(C3=CC=C(C([H])=O)C=C3)=O)=O)C=C2)N=N1
Biological Activity: Methyltetrazine-PEG4-aldehyde is a cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. Methyltetrazine-PEG4-aldehyde is a click chemistry reagent, it contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups.
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Methyltetrazine-PEG4-aldehyde | Methyltetrazine-PEG4-aldehyde is a cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Methyltetrazine-PEG4-aldehyde is a click chemistry reagent, it contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups. | |||||||||||||||||||||
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Keywords
