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P-gp-IN-32

P-gp-IN-32 is a P-glycoprotein (P-gp) inhibitor. P-gp-IN-32 exhibits low cytotoxicity and potent multidrug resistance (MDR) reversal activity against Doxorubicin (HY-15142A) in MCF7/ADR cells (IC50 = 0.11 μM, reversal fold (RF) = 215.9). P-gp-IN-32 can bind to P-gp directly, induce a conformation change of P-gp and inhibit the efflux function. P-gp-IN-32 can be used for the research of cancer, such as breast cancer.

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  • CAS No.: 2918249-59-7
  • Formule: C35H34N2O5
  • Masse moléculaire:562.65
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    Please store the product under the recommended conditions in the Certificate of Analysis.

  • P-gp-IN-32 Chemical Structure
    P-gp-IN-32 Chemical Structure
CAS No.: 2918249-59-7
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  • P-gp-IN-32 Chemical Structure
    P-gp-IN-32 Chemical Structure
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  • P-gp-IN-32