Copy Link Print Information

Palverafusp alfa

(Synonyms: IMM-2510; SYN-2510)
Avis client

Based on 1 Customer Validation

Palverafusp alfa (IMM-2510; SYN-2510) is a PD-L1/VEGF-targeting IgG1κ type humanized antibody. Palverafusp alfa blocks PD-1/PD-L1 binding, relieves immune suppression, mediates PD-L1-directed antibody-dependent cellular cytotoxicity (ADCC). Palverafusp alfa blocks VEGF/VEGFR binding, inhibits angiogenic signaling, relieves VEGF-induced immune suppression. Palverafusp alfa reduces endothelial cell proliferation, enhances ADCC and antibody-dependent cellular phagocytosis (ADCP), inhibits tumor growth, reverses T cell immune suppression. Palverafusp alfa exhibits immune stimulatory, antiangiogenic, and anti-tumor activity in the tumor microenvironment. Palverafusp alfa can be used for the research of cancer, such as solid tumors, non-small cell lung cancer.

Nos produits utilisent uniquement pour la recherche. Nous ne vendons pas aux patients.

  • Pureté: 98.00%
  • CAS No.: 2850355-87-0
  • Masse moléculaire:169.11 kDa
  • Stockage:

    Please store the product under the recommended conditions in the Certificate of Analysis.

  • Experimental Validation Results for Palverafusp alfa
  • Experimental Validation Results for Palverafusp alfa
  • Palverafusp alfa Chemical Structure
    Palverafusp alfa Chemical Structure
CAS No.: 2850355-87-0
Size
Prix
Stock
Quantité
Amount: USD 0.00
Please select quantity
or
or

* Veuillez sélectionner la quantité avant d'ajouter des articles.

To place orders, for customer services and technical support, please contact: MedChemExpress USA

Tel: 609-228-6898 E-mail: [email protected] [email protected]

Data Download
Palverafusp alfa Product Recommendations:

To place orders, for customer services and technical support, please contact:

609-228-6898
[email protected] [email protected]
Trouvez votre distributeur local Your local distributor: Hycultec GmbHHycultec
  • Activité biologique
  • Chemical Information
  • Pureté et documentation
  • Références
  • Help & FAQs
You May Still Need
Top Publications Citing

Use of MCE Products

Voir tous les produits spécifiques à Isoform VEGFR

More
Keywords
MOQ
Minimum order quantity
100 mg

Obtenir un devis En stock

Other size
Obtenir un devis
Please select quantity
Amount: USD 0.00
Sign in to MedChemExpress Sign In
Enregistrer
Sign in to MedChemExpress
Enregistrer un nouveau compte

At least 6 characters

Personalize your experience, you are currently not signed in. For a better experience, please create an online profile, you can:

Obtain points redemption prizes
Check out faster
Add multiple shipping locations
View orders
Assay Types
  • 1/16

    IgG1-kappa-[PROTEIN]2-in-VH

  • 1/16

    Loaded Palverafusp alfa on AHC2 biosensor, can bind VEGF121 Protein, Human (HEK293, His, HY-P70519) with an affinity constant of 2.310E-10 M as determined in BLI assay.

  • Palverafusp alfa Chemical Structure
    1/16
  • Palverafusp alfa
  • Loaded Palverafusp alfa on AHC2 biosensor, can bind VEGF121 Protein, Human (HEK293, His, HY-P70519) with an affinity constant of 2.310E-10 M as determined in BLI assay.
  • IgG1-kappa-[PROTEIN]2-in-VH