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Zifibancimig

(Synonyms: RO-7250284)
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Zifibancimig (RO-7250284) is a monoclonal antibody against VEGF-A and Ang-2, with affinities of 4 pM and 2 pM, respectively. Zifibancimig has high stability, maintains target-binding capability under physiological stress and storage conditions, and is designed for sustained long-term ocular delivery via the Port Delivery implant device. Zifibancimig can be used in the research of retinal diseases.

Nos produits utilisent uniquement pour la recherche. Nous ne vendons pas aux patients.

  • Pureté: 99.00%
  • CAS No.: 2517939-46-5
  • Masse moléculaire:47.921 kDa
  • Stockage:

    Please store the product under the recommended conditions in the Certificate of Analysis.

  • Experimental Validation Results for Zifibancimig
  • Experimental Validation Results for Zifibancimig
  • Experimental Validation Results for Zifibancimig
  • Experimental Validation Results for Zifibancimig
  • Zifibancimig Chemical Structure
    Zifibancimig Chemical Structure
CAS No.: 2517939-46-5
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Zifibancimig Product Recommendations:

To place orders, for customer services and technical support, please contact:

609-228-6898
[email protected] [email protected]
Trouvez votre distributeur local Your local distributor: Hycultec GmbHHycultec
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Assay Types
  • 1/16

    Fab-G1-kappa

  • 1/16

    Loaded Zifibancimig on FAB2G biosensor, can bind VEGF121 Protein, Human (120 a.a, HY-P7420) with an affinity constant of <1.000E-11 M as determined in BLI assay.

  • 1/16

    Loaded Zifibancimig on FAB2G biosensor, can bind Angiopoietin-2 Protein, Human (222a.a, HEK293, His, HY-P7510) with an affinity constant of 2.091E-09 M as determined in BLI assay.

  • 1/16

    Flow cytometric analysis of 1X106 HeLa cells with Zifibancimig (HY-P990689, red). Cells were fixed with 4% paraformaldehyde. Then stained with the primary antibody at 1/200 dilution for an hour at 4℃. AF 488-conjugated AffiniPure Goat Anti-Human IgG H&L (HY-P83776) was used as the secondary antibody at 1/1,000 dilution for 30 minutes at 4℃. Human IgG1 kappa (HY-P99001, blue) was used as the isotype control, cells without incubation with primary antibody were used as the unlabeled control (black).

  • Zifibancimig Chemical Structure
    1/16
  • Zifibancimig
  • Loaded Zifibancimig on FAB2G biosensor, can bind VEGF121 Protein, Human (120 a.a, HY-P7420) with an affinity constant of <1.000E-11 M as determined in BLI assay.
  • Loaded Zifibancimig on FAB2G biosensor, can bind Angiopoietin-2 Protein, Human (222a.a, HEK293, His, HY-P7510) with an affinity constant of 2.091E-09 M as determined in BLI assay.
  • Flow cytometric analysis of 1X106 HeLa cells with Zifibancimig (HY-P990689, red). Cells were fixed with 4% paraformaldehyde. Then stained with the primary antibody at 1/200 dilution for an hour at 4℃. AF 488-conjugated AffiniPure Goat Anti-Human IgG H&L (HY-P83776) was used as the secondary antibody at 1/1,000 dilution for 30 minutes at 4℃. Human IgG1 kappa (HY-P99001, blue) was used as the isotype control, cells without incubation with primary antibody were used as the unlabeled control (black).
  • Fab-G1-kappa