517-63-5
Chemical Structure
Stephanine
Synonym(s): (-)-Stephanine; l-Stephanine
- CAS No.: 517-63-5
- Formula:C19H19NO3
- Molecular Weight:309.36
IUPAC Name: (R)-9-methoxy-7-methyl-6,7,7a,8-tetrahydro-5H-[1,3]dioxolo[4',5':4,5]benzo[1,2,3-de]benzo[g]quinoline
InChIKey: UEAPAHNNFSZHMW-CQSZACIVSA-N
SMILES: CN1CCC(C2=C3C4=CC=CC(OC)=C4C[C@@]12[H])=CC5=C3OCO5
Biological Activity: Stephanine ((-)-Stephanine) is an isoquinoline aporphine-type alkaloid. Stephanine induce apoptosis through the reverse of mitotic exit. Stephanine exhibits Antiplasmodial activity. Stephanine can be used for the research of stomach pain, abdominal pain, arthritis and cancer[1][2].
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Stephanine | Stephanine ((-)-Stephanine) is an isoquinoline aporphine-type alkaloid. Stephanine induce apoptosis through the reverse of mitotic exit. Stephanine exhibits Antiplasmodial activity. Stephanine can be used for the research of stomach pain, abdominal pain, arthritis and cancer. | |||||||||||||||||||||
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- [1]. Cui L, et, al. The anti-inflammatory and analgesic activities of 2Br-Crebanine and Stephanine from Stephania yunnanenses H. S.Lo. Front Pharmacol. 2023 Jan 4;13:1092583. [Content Brief]
- [2]. Le PM, et, al. Stephanine from Stephania venosa (Blume) Spreng Showed Effective Antiplasmodial and Anticancer Activities, the Latter by Inducing Apoptosis through the Reverse of Mitotic Exit. Phytother Res. 2017 Sep;31(9):1357-1368. [Content Brief]
Keywords
