Copy Link Print Information

BIBO3304 free base

4 Cited Publications
Kundenbewertung

Based on 4 publication(s) in Google Scholar

BIBO3304 free base is a nonpeptide neuropeptide Y Y1 receptor antagonist. BIBO3304 free base displays subnanomolar affinity for both the human and the rat Y1 receptor, with IC50 values of 0.38 nM and 0.72 nM, respectively. BIBO3304 free base significantly inhibits food intake induced by application of NPY or by fasting.

Nur für Forschungszwecke. Wir verkaufen nicht an Patienten.

  • CAS. Nr.: 191868-13-0
  • Formel: C29H35N7O3
  • Molecular Weight:529.63
  • Speicherung:

    Please store the product under the recommended conditions in the Certificate of Analysis.

  • BIBO3304 free base Chemical Structure
    BIBO3304 free base Chemical Structure
  • Experimental Validation Results for BIBO3304 free base
  • Experimental Validation Results for BIBO3304 free base
  • Experimental Validation Results for BIBO3304 free base
CAS. Nr.: 191868-13-0
Größe
Preis
Verfügbarkeit
Menge
Amount: USD 0.00
Please select quantity
or
or

* Bitte wählen Sie Menge, bevor Sie Artikel hinzufügen.

To place orders, for customer services and technical support, please contact: MedChemExpress USA

Tel: 609-228-6898 E-mail: [email protected] [email protected]

Data Download
Other Forms of BIBO3304 free base:

To place orders, for customer services and technical support, please contact:

609-228-6898
[email protected] [email protected]
Finden Sie Ihren Händler vor Ort Your local distributor: Hycultec GmbHHycultec
  • Biologische Aktivität
  • Chemical Information
  • Reinheit & Dokumentation
  • Verweise
  • Help & FAQs
Top Publications Citing

Use of MCE Products

Publications Citing Use of MedChemExpress (MCE) BIBO3304 free base

More
Customer Validation & Images
OthersIn Vivo Efficacy Study
  • Others
  • In Vivo Efficacy Study
  • Others

Alle Neuropeptide Y Receptor Isoform-spezifische Produkte anzeigen

More
Keywords
MOQ
Minimum order quantity
100 mg

Angebot einholen Auf Lager

Other size
Angebot einholen
Please select quantity
Amount: USD 0.00
Sign in to MedChemExpress Einloggen
Registrieren
Sign in to MedChemExpress
Neuen Account Registrieren

At least 6 characters

Personalize your experience, you are currently not signed in. For a better experience, please create an online profile, you can:

Obtain points redemption prizes
Check out faster
Add multiple shipping locations
View orders
Assay Types
  • BIBO3304 free base Chemical Structure
    BIBO3304 free base Chemical Structure
    1/16
  • 1/16

    BIBO3304 free base purchased from MedChemExpress. Usage Cited in: Nat Commun. 2025 Aug 1;16(1):7074. [Abstract]

    Customer Validation
     Intrathecal injection of NPY1R selective antagonist BIBO3304 (BIBO, 10 μg, 20 min before) blocked the effects of LP-NPY (3 μg) on morphine-induced itch, one-way ANOVA, Dunnett’s multiple comparisons.

  • 1/16

    BIBO3304 free base purchased from MedChemExpress. Usage Cited in: Nat Commun. 2025 Aug 1;16(1):7074. [Abstract]

    Customer Validation
     NPY (10 μM) induced outward currents were recorded and inhibited by BIBO3304(2 μM) from GRP+ interneurons in the SDH from GrpCre;Ai9 mice.

  • 1/16

    BIBO3304 free base purchased from MedChemExpress. Usage Cited in: In Vivo. 2024 May-Jun;38(3):1133-1142. [Abstract]

    Customer Validation
     Hypothalamic NPY exerted an antinociceptive effect by binding to Y1R and Y2R in cancer-bearing rats. PWT was measured using von Frey filaments (BIBO3304: 3 μg).

  • BIBO3304 free base