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Girentuximab

(Synonyms: G250; cG250)
1 Cited Publications
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Based on 1 publication(s) in Google Scholar

Girentuximab (G250) is a chimeric monoclonal antibody that binds carbonic anhydrase IX (CAIX), a cell surface glycoprotein ubiquitously expressed in clear cell renal cell carcinoma (ccRCC).

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  • Reinheit: 99.90%
  • CAS. Nr.: 916138-87-9
  • Molecular Weight:144.62 kDa
  • Speicherung:

    Please store the product under the recommended conditions in the Certificate of Analysis.

  • Experimental Validation Results for Girentuximab
  • Experimental Validation Results for Girentuximab
  • Experimental Validation Results for Girentuximab
  • Girentuximab Chemical Structure
    Girentuximab Chemical Structure
CAS. Nr.: 916138-87-9
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To place orders, for customer services and technical support, please contact:

609-228-6898
[email protected] [email protected]
Finden Sie Ihren Händler vor Ort Your local distributor: Hycultec GmbHHycultec
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Assay Types
  • 1/16

    Human IgG1 kappa

  • 1/16

    Immobilized Carbonic Anhydrase 9 Protein, Canine (HEK293, His, HY-P75454) can bind Girentuximab. The EC50 for this effect is 26.65 ng/mL.

  • 1/16

    Flow cytometric analysis of 1.5×106 HT-29 cells with Girentuximab (HY-P99023, red). Cells were fixed with 4% paraformaldehyde and permeabilised with 90% methanol. Then stained with the primary antibody at 1/200 dilution for an hour at 4℃. Alexa Goat Anti-Human IgG H&L (AF488) (HY-P83776) was used as the secondary antibody at 1/1,000 dilution for 30 minutes at 4℃. Human IgG1 kappa Isotype Control (HY-P99001, blue) was used as the isotype control.

  • Girentuximab Chemical Structure
    1/16
  • Girentuximab
  • Immobilized Carbonic Anhydrase 9 Protein, Canine (HEK293, His, HY-P75454) can bind Girentuximab. The EC50 for this effect is 26.65 ng/mL.
  • Flow cytometric analysis of 1.5×106 HT-29 cells with Girentuximab (HY-P99023, red). Cells were fixed with 4% paraformaldehyde and permeabilised with 90% methanol. Then stained with the primary antibody at 1/200 dilution for an hour at 4℃. Alexa Goat Anti-Human IgG H&L (AF488) (HY-P83776) was used as the secondary antibody at 1/1,000 dilution for 30 minutes at 4℃. Human IgG1 kappa Isotype Control (HY-P99001, blue) was used as the isotype control.