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Art. -Nr.: HY-124378

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MAGL-IN-17

Name: MAGL-IN-17
Brand: MedChemExpress
SKU: HY-124378
Price: 154.00 USD
Availability: InStock
Rating: 5 (1 reviews)

MAGL-IN-17 (Compound ) is an inhibitor for MAGL with a K_i of 0.4 μM. MAGL-IN-17 inhibits mouse MAGL and rat MAGL with IC₅₀ of 0.18 and 0.24 μM. MAGL-IN-17 exhibits anti-inflammatory activity in mouse experimental autoimmune encephalitis models.

Nur für Forschungszwecke. Wir verkaufen nicht an Patienten.

CAS. Nr.: 1643657-35-5
Formel: C₂₆H₂₆O₄
Molecular Weight:402.48

Speicherung:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (264 KB)

MAGL-IN-17 Chemical Structure

CAS. Nr.: 1643657-35-5

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biologische Aktivität
- Beschreibung
- IC₅₀ & Target
- Cellular Effect
Chemical Information
Reinheit & Dokumentation
Verweise
Calculators
Help & FAQs
Classifications
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Biologische Aktivität

Beschreibung

IC₅₀ & Target

K_i: 0.4 μM (MAGL)

Cellular Effect

Cell Line	Type	Value	Description	References
Caov-3 cell line	IC₅₀	>200 μM Compound: 3	Antiproliferative activity against human Caov-3 cells assessed as reduction in cell viability incubated for 96 hrs by Cell-titer-Glo luminescent cell viability assay Antiproliferative activity against human Caov-3 cells assessed as reduction in cell viability incubated for 96 hrs by Cell-titer-Glo luminescent cell viability assay	[PMID: 27809504]
MRC5	IC₅₀	>200 μM Compound: 3	Antiproliferative activity against human MRC5 cells assessed as reduction in cell viability incubated for 96 hrs by Cell-titer-Glo luminescent cell viability assay Antiproliferative activity against human MRC5 cells assessed as reduction in cell viability incubated for 96 hrs by Cell-titer-Glo luminescent cell viability assay	[PMID: 27809504]
OVCAR-3	IC₅₀	110 μM Compound: 3	Antiproliferative activity against human OVCAR-3 cells assessed as reduction in cell viability incubated for 96 hrs by Cell-titer-Glo luminescent cell viability assay Antiproliferative activity against human OVCAR-3 cells assessed as reduction in cell viability incubated for 96 hrs by Cell-titer-Glo luminescent cell viability assay	[PMID: 27809504]

Chemical Information

CAS. Nr. 1643657-35-5
Molecular Weight 402.48
Formel C₂₆H₂₆O₄
SMILES

O=C(CCCCCC1=CC=C(C2=CC=CC=C2)C=C1)OCC3=CC4=C(C=C3)OCO4
Versand

Room temperature in continental US; may vary elsewhere.
Speicherung

Please store the product under the recommended conditions in the Certificate of Analysis.

Reinheit & Dokumentation

Select Batch:

Reinheit: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (264 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

Verweise

[1]. Hernández-Torres G, et al., A reversible and selective inhibitor of monoacylglycerol lipase ameliorates multiple sclerosis. Angew Chem Int Ed Engl. 2014 Dec 8;53(50):13765-70. [Content Brief]

Calculators

Molaritätsrechner

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Konzentration Konzentration

Volumen Volumen

Molecular Weight Molecular Weight

Verdünnungsrechner

Konzentration _{(Stammlösung)} × Volumen _{(Stammlösung)} = Konzentration _{(Ziellösung)} × Volumen _{(Ziellösung)}

Konzentration _{(Stammlösung)} Konzentration _{(Stammlösung)}

Volumen _{(Stammlösung)} Volumen _{(Stammlösung)}

Konzentration _{(Ziellösung)} Konzentration _{(Ziellösung)}

Volumen _{(Ziellösung)} Volumen _{(Ziellösung)}

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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Keywords

MOQ

Minimum order quantity

100 mg

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Biologische Aktivität
- Beschreibung
- IC₅₀ & Target
Chemical Information
Reinheit & Dokumentation
Verweise

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MAGL-IN-17

Oleoyl ethyl amide

JZL 184

JW 642

MJN110

JZL195

1,1,1-Trifluoro-10(Z)-nonadecen-2-one

KML29

TC-F2

JW 642 (Standard)

JNJ-42165279

JNJ-1661010

JZL 184 (Standard)

Biologische Aktivität

Chemical Information

Reinheit & Dokumentation

Verweise

Calculators

Help & FAQs

Bioz

MAGL-IN-17

Oleoyl ethyl amide

JZL 184

JW 642

MJN110

JZL195

1,1,1-Trifluoro-10(Z)-nonadecen-2-one

KML29

TC-F2

JW 642 (Standard)

JNJ-42165279

JNJ-1661010

JZL 184 (Standard)

Biologische Aktivität

Chemical Information

Reinheit & Dokumentation

Verweise

Calculators

Help & FAQs

MAGL-IN-17 Related Classifications

HY-124378 Related Classifications

Bioz