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Art. -Nr.: HY-184026

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MAO-B-IN-58

MAO-B-IN-58 (Compound 2e) is a reversible, selective MAO-B inhibitor with an IC₅₀ of 170 nM against rat MAO-B. MAO-B-IN-58 is applicable for the research of Parkinson's disease and Alzheimer's disease.

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CAS. Nr.: 898540-68-6
Formel: C₁₉H₁₄N₂O₂
Molecular Weight:302.33

Speicherung:

Please store the product under the recommended conditions in the Certificate of Analysis.

MAO-B-IN-58 Chemical Structure

CAS. Nr.: 898540-68-6

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Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biologische Aktivität
- Beschreibung
- IC₅₀ & Target
- In Vitro
Chemical Information
Reinheit & Dokumentation
Verweise
Calculators
Help & FAQs
Classifications
Bioz

Biologische Aktivität

Beschreibung

IC₅₀ & Target^[1]

MAO-B

170 nM (IC₅₀)

MAO-A

>1000 nM (IC₅₀)

Alle Monoamine Oxidase Isoform-spezifische Produkte anzeigen :

MAO-A
MAO-B

In Vitro

MAO-B-IN-58 potently inhibits MAO-B in rat brain mitochondria with an IC₅₀ of 170 nM and does not inhibit MAO-A^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS. Nr. 898540-68-6
Molecular Weight 302.33
Formel C₁₉H₁₄N₂O₂
SMILES

CC1=CC2=C(C3=CC(OCC4=CC=CC=C4)=CC=C3C2=O)N=N1
Versand

Room temperature in continental US; may vary elsewhere.
Speicherung

Please store the product under the recommended conditions in the Certificate of Analysis.

Reinheit & Dokumentation

Handling Instructions (2659 KB)

Verweise

[1]. Frédérick R, et al. Synthesis, structural reassignment, and biological activity of type B MAO inhibitors based on the 5H-indeno[1,2-c]pyridazin-5-one core. J Med Chem. 2006 Jun 15;49(12):3743-7. [Content Brief]

Calculators

Molaritätsrechner

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Konzentration Konzentration

Volumen Volumen

Molecular Weight Molecular Weight

Verdünnungsrechner

Konzentration _{(Stammlösung)} × Volumen _{(Stammlösung)} = Konzentration _{(Ziellösung)} × Volumen _{(Ziellösung)}

Konzentration _{(Stammlösung)} Konzentration _{(Stammlösung)}

Volumen _{(Stammlösung)} Volumen _{(Stammlösung)}

Konzentration _{(Ziellösung)} Konzentration _{(Ziellösung)}

Volumen _{(Ziellösung)} Volumen _{(Ziellösung)}

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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Biologische Aktivität
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- IC₅₀ & Target
- In Vitro
Chemical Information
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MAO-B-IN-58

Alle Monoamine Oxidase Isoform-spezifische Produkte anzeigen

Biologische Aktivität

Chemical Information

Reinheit & Dokumentation

Verweise

Calculators

Help & FAQs

MAO-B-IN-58 Related Classifications

HY-184026 Related Classifications