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Art. -Nr.: HY-N19842

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Neomethymycin

Neomethymycin (Compound5) is a 12-membered ring macrolide natural product. Neomethymycin can be found in engineered Streptomyces venezuelae ATCC 15439 strain DHS2001, where it forms via biotransformation of 10-deoxymethyonolide.

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CAS. Nr.: 497-73-4
Formel: C₂₅H₄₃NO₇
Molecular Weight:469.61

Speicherung:

Please store the product under the recommended conditions in the Certificate of Analysis.

Neomethymycin Chemical Structure

CAS. Nr.: 497-73-4

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- In Vitro
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Biologische Aktivität

Beschreibung

IC₅₀ & Target^[1]

Microbial Metabolite

Alle Endogenous Metabolite Isoform-spezifische Produkte anzeigen :

In Vitro

Neomethymycin (sufficient time to yield product; assessed over culture growth phase) is predominately produced alongside methymycin via biotransformation of 10-deoxymethyonolide by pre-log phase cultures of Streptomyces venezuelae strain DHS2001, with a combined methymycin product yield of 66% (15% overall from (R)-Roche ester)^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS. Nr. 497-73-4
Molecular Weight 469.61
Formel C₂₅H₄₃NO₇
SMILES

O[C@H]([C@H](C[C@H](O1)C)N(C)C)[C@@H]1O[C@@H]2[C@H](C(O[C@]([C@@H](/C=C/C([C@@H](C[C@@H]2C)C)=O)C)([H])[C@H](O)C)=O)C
Structure Classification
- Others
Initial Source
- Microorganisms
Streptomyces venezuelae
Versand

Room temperature in continental US; may vary elsewhere.
Speicherung

Please store the product under the recommended conditions in the Certificate of Analysis.

Reinheit & Dokumentation

Handling Instructions (2659 KB)

Verweise

[1]. Hansen DA, et al. Biocatalytic synthesis of pikromycin, methymycin, neomethymycin, novamethymycin, and ketomethymycin. J Am Chem Soc. 2013;135(30):11232-11238. [Content Brief]

Calculators

Molaritätsrechner

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Konzentration Konzentration

Volumen Volumen

Molecular Weight Molecular Weight

Verdünnungsrechner

Konzentration _{(Stammlösung)} × Volumen _{(Stammlösung)} = Konzentration _{(Ziellösung)} × Volumen _{(Ziellösung)}

Konzentration _{(Stammlösung)} Konzentration _{(Stammlösung)}

Volumen _{(Stammlösung)} Volumen _{(Stammlösung)}

Konzentration _{(Ziellösung)} Konzentration _{(Ziellösung)}

Volumen _{(Ziellösung)} Volumen _{(Ziellösung)}

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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Neomethymycin

Alle Endogenous Metabolite Isoform-spezifische Produkte anzeigen

Biologische Aktivität

Chemical Information

Reinheit & Dokumentation

Verweise

Calculators

Help & FAQs

Neomethymycin Related Classifications

HY-N19842 Related Classifications